Evidence map›Paper›PMID 36697721›Full record

ReviewPediatric radiology2023

Unexpected extracardiac findings in cardiac computed tomography from neonates to young adults.

Daniel J Sassoon, Evan C Norris, LaDonna J Malone, Jason P Weinman, David A Mong, Alex J Barker, Lorna P Browne

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Daniel J SassoonDepartment of Radiology, University of Colorado, Aurora, CO, USA.
Evan C NorrisDepartment of Radiology, University of Colorado, Aurora, CO, USA.
LaDonna J MaloneDepartment of Radiology, Children's Hospital Colorado, University of Colorado, 13123 E. 16th Ave., Box 125, Aurora, CO, 80045, USA.
Jason P WeinmanDepartment of Radiology, Children's Hospital Colorado, University of Colorado, 13123 E. 16th Ave., Box 125, Aurora, CO, 80045, USA.
David A MongDepartment of Radiology, Children's Hospital Colorado, University of Colorado, 13123 E. 16th Ave., Box 125, Aurora, CO, 80045, USA.
Alex J BarkerDepartment of Radiology, Children's Hospital Colorado, University of Colorado, 13123 E. 16th Ave., Box 125, Aurora, CO, 80045, USA.
Lorna P BrowneDepartment of Radiology, Children's Hospital Colorado, University of Colorado, 13123 E. 16th Ave., Box 125, Aurora, CO, 80045, USA. Lorna.browne@childrenscolorado.org.
Children's Hospital Colorado · USUniversity of Colorado Denver · USUniversity of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundModern CT scanners with lower radiation doses have resulted in large numbers of cardiac CTs being performed in children. As seen in adults, pediatric cardiac CT has the potential to demonstrate extracardiac variants and pathology that can occur in conjunction with congenital heart disease (CHD). Prior publications demonstrated a high incidence of extracardiac findings in various locations but the prevalence of urgent unexpected extracardiac findings in children is unknown.

objectiveThe purpose of this study was to describe the incidence, distribution and clinical significance of the extracardiac findings on pediatric cardiac CT at a tertiary referral center. MATERIALS AND

methodsWe reviewed all reports (n = 648) for 554 children through young adults who received a cardiac CT study between Jan. 2, 2018, and March 10, 2020, at our tertiary referral pediatric hospital. We interrogated CT reports for extracardiac findings and categorized them by system (airway, pulmonary, abdomen, malpositioned lines and musculoskeletal). We then subclassified each of these findings by level of clinical importance based upon the need for intervention or treatment into low, medium or high importance. High-importance findings were confirmed with a focused chart review. If a patient had more than one CT with a persistent extracardiac finding, the finding was only counted once.

resultsWe identified 562 individual extracardiac findings, with one or more extracardiac findings present in 91% of the study population. Extracardiac findings with high clinical importance, requiring urgent attention or intervention, were present in 10% (57/554) of cases. The most common location of extracardiac findings was pulmonary (50%; 280/562), followed by airway (22%; 125/562) and abdomen (9%; 52/562).

conclusionUnexpected highly important extracardiac findings were found in 10% of patients. Therefore, extracardiac structures should be scrutinized for the timely identification of potentially highly important findings.

Indexed as

Heart Defects, CongenitalTomography, X-Ray ComputedChildHeartHumansInfant, NewbornPrevalenceRetrospective StudiesYoung AdultChildrenComputed tomographyCongenital heart diseaseExtracardiacIncidental findingYoung adults

Identifiers

PMID36697721
OpenAlexW4318035627

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.