ArticleCommunications chemistry2021
Conformer-dependent vacuum ultraviolet photodynamics and chiral asymmetries in pure enantiomers of gas phase proline.
Article in Communications chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Chiral Micellar Assemblies for Circularly Polarized Luminescence Amplification, Dye Encapsulation, and Multilevel Information Encryption.Angewandte Chemie (International ed. in English) · 2026Article
- Spectroscopy and Conformer-Selective Photoelectron Circular Dichroism of Chiral Molecules.Chemistry, an Asian journal · 2026Review
- Conformer-resolved ultrafast chemical dynamics observed at ambient temperature.Science advances · 2026Article
- Induced Photoelectron Circular Dichroism as a Probe for Distinguishing Diastereotopic Lone Electron Pairs.Angewandte Chemie (International ed. in English) · 2026Article
- Linking photoelectron circular dichroism to the asymmetric total photoemission yield measured in aerosol nanoparticles of tyrosine.Nature communications · 2026Article
- Photoelectron spectroscopy and circular dichroism of an open-shell organometallic camphor complex.Structural dynamics (Melville, N.Y.) · 2026Article
- Conformer-selective photoelectron circular dichroism: Experimental development and application to nitrogen chirality.Structural dynamics (Melville, N.Y.) · 2025Article
- Photoelectron Circular Dichroism in the Photodetachment of Deprotonated 1-Phenylethanol.The journal of physical chemistry letters · 2025Article
- Induced photoelectron circular dichroism onto an achiral chromophore.Nature communications · 2023Article
- Fast and precise chiroptical spectroscopy by photoelectron elliptical dichroism.Physical chemistry chemical physics : PCCP · 2023Article
- Enantiomeric Excesses of Aminonitrile Precursors Determine the Homochirality of Amino Acids.The journal of physical chemistry letters · 2023Article
- Imaging Photoelectron Circular Dichroism in the Detachment of Mass-Selected Chiral Anions.Angewandte Chemie (International ed. in English) · 2023Article
- Amino acid gas phase circular dichroism and implications for the origin of biomolecular asymmetry.Nature communications · 2022Article
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Authors and funding
6 authors.
Funding
Abstract
Proline is a unique amino-acid, with a secondary amine fixed within a pyrrolidine ring providing specific structural properties to proline-rich biopolymers. Gas-phase proline possesses four main H-bond stabilized conformers differing by the ring puckering and carboxylic acid orientation. The latter defines two classes of conformation, whose large ionization energy difference allows a unique conformer-class tagging via electron spectroscopy. Photoelectron circular dichroism (PECD) is an intense chiroptical effect sensitive to molecular structures, hence theorized to be highly conformation-dependent. Here, we present experimental evidence of an intense and striking conformer-specific PECD, measured in the vacuum ultraviolet (VUV) photoionization of proline, as well as a conformer-dependent cation fragmentation behavior. This finding, combined with theoretical modeling, allows a refinement of the conformational landscape and energetic ordering, that proves inaccessible to current molecular electronic structure calculations. Additionally, astrochemical implications regarding a possible link of PECD to the origin of life's homochirality are considered in terms of plausible temperature constraints.
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