Evidence map›Paper›PMID 36697369›Full record

ArticleAnnals of the New York Academy of Sciences2023

Positive-strand RNA viruses-a Keystone Symposia report.

Jennifer Cable, Mark R Denison, Margaret Kielian, William T Jackson, Ralf Bartenschlager, Tero Ahola, Suchetana Mukhopadhyay, Daved H Fremont, Richard J Kuhn, Ashleigh Shannon and 35 more

Abstract read
In one paragraph

Article in Annals of the New York Academy of Sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors.

Jennifer CablePhD Science Writer, New York, New York, USA.
Mark R DenisonDepartment of Pediatrics and Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center; and Vanderbilt Institute for Infection, Immunology, and Inflammation, Nashville, Tennessee, USA.
Margaret KielianDepartment of Cell Biology, Albert Einstein College of Medicine, New York, New York, USA.
William T JacksonDepartment of Microbiology and Immunology and Center for Pathogen Research, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Ralf BartenschlagerDepartment of Infectious Diseases, Molecular Virology, Heidelberg University and German Cancer Research Center (DKFZ), Research Division Virus-associated Carcinogenesis, Heidelberg, Germany.
Tero AholaDepartment of Microbiology, Faculty of Agriculture and Forestry, University of Helsinki, Helsinki, Finland.
Suchetana MukhopadhyayDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Daved H FremontDepartment of Pathology & Immunology; Department of Molecular Microbiology; and Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, USA.
Richard J KuhnDepartment of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.
Ashleigh ShannonArchitecture et Fonction des Macromolécules Biologiques, CNRS and Aix Marseille Université, Marseille, France.
Meredith N FrazierSignal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA.
Kwok-Yung YuenDepartment of Microbiology, Li Ka Shing Faculty of Medicine and State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, People's Republic of China.
Carolyn B CoyneDepartment of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, USA.
Katja C WolthersDepartment of Medical Microbiology, Amsterdam UMC, University of Amsterdam and Amsterdam Institute for Infection and Immunity, OrganoVIR Labs, Amsterdam, The Netherlands.
Guo-Li MingDepartment of Neuroscience and Mahoney Institute for Neurosciences, Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Camy S GuentherColorado State University, Fort Collins, Colorado, USA.
Jasmine MoshiriDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.
Sonja M BestLaboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
John W SchogginsDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kellie Ann JuradoDepartment of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Gregory D EbelCenter for Vector-borne Infectious Diseases, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Alexandra SchäferDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Lisa F P NgASTAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science Technology and Research (A*STAR), Singapore City, Singapore.
Marjolein KikkertDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
Alessandro SetteCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology, La Jolla, California, USA.
Eva HarrisDivision of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, California, USA.
Peter A C WingNuffield Department of Medicine and Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK.
Julie EggenbergerDepartment of Immunology, University of Washington School of Medicine, Seattle, Washington, USA.
Siddharth R KrishnamurthyMetaorganism Immunity Section, Laboratory of Immune System Biology and NIAID Microbiome Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Marcus G MahProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore City, Singapore.
Rita M MeganckDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Donghoon ChungDepartment of Experimental Therapeutics, MD Anderson Cancer Center, Houston, Texas, USA.
Sebastian Maurer-StrohYong Loo Lin School of Medicine and Department of Biological Sciences, National University of Singapore, Singapore City, Singapore.
Raul AndinoDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.
Bette KorberLos Alamos National Laboratory, Los Alamos, New Mexico, USA.
Stanley PerlmanDepartment of Microbiology and Immunology, and Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA.
Pei-Yong ShiDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, USA.
Montserrat BárcenaSection Electron Microscopy, Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands.
Sophie-Marie AicherInstitut Pasteurgrid, Université de Paris Cité, Virus Sensing and Signaling Unit, Paris, France.
Michelle N VuDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Devin J KenneyDepartment of Microbiology and National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston, Massachusetts, USA.
Brett D LindenbachDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, Connecticut, USA.
Yukiko NishidaChugai Pharmaceutical, Co., Tokyo, Japan.
Laurent RéniaASTAR Infectious Diseases Labs (A*STAR ID Labs), Agency for Science Technology and Research (A*STAR), Singapore City, Singapore.
Evan P WilliamsDepartment of Microbiology, Immunology, and Biochemistry, The University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Virus-Host Interactions: Induction and Evasion of Host Innate ImmunityZIAAI001125 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BEST, SONJA · 2010 to 2025
$28.1M
SARS-CoV Proteins in Heterologous Viral InfectionP01AI060699 · NIAID · UNIVERSITY OF IOWA · PI PERLMAN, STANLEY · 2004 to 2021
$21.5M
VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
Molecular Analysis of Alphavirus Membrane Fusion ProteinR01AI075647 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KIELIAN, MARGARET · 2007 to 2023
$9.0M
Role of eicosanoids in pathogenic human CoV infectionsR01AI129269 · NIAID · UNIVERSITY OF IOWA · PI Stanley Perlman · 2016 to 2026
$4.7M
The roles of acidic autophagosomes in production of infectious poliovirusR01AI104928 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI JACKSON, WILLIAM T · 2014 to 2023
$3.8M
Enterovirus manipulation of autophagic trafficking pathwaysR01AI141359 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI JACKSON, WILLIAM T · 2019 to 2022
$1.5M
Characterization of a human-specific positive regulator of flavivirus infectionK22AI144050 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI DOUAM, FLORIAN · 2021 to 2023
$344k
NCATS NIH HHS UL1 TR001430NIAID NIH HHS K22 AI144050NIAID NIH HHS P01 AI060699NIAID NIH HHS R01 AI075647NIAID NIH HHS R01 AI104928NIAID NIH HHS R01 AI129269NIAID NIH HHS R01 AI141359NIAID NIH HHS T32 AI007140NIH HHS K22 AI144050
6 · The paper itself

Abstract

Positive-strand RNA viruses have been the cause of several recent outbreaks and epidemics, including the Zika virus epidemic in 2015, the SARS outbreak in 2003, and the ongoing SARS-CoV-2 pandemic. On June 18-22, 2022, researchers focusing on positive-strand RNA viruses met for the Keystone Symposium "Positive-Strand RNA Viruses" to share the latest research in molecular and cell biology, virology, immunology, vaccinology, and antiviral drug development. This report presents concise summaries of the scientific discussions at the symposium.

Indexed as

COVID-19Zika VirusZika Virus InfectionAntiviral AgentsHumansPandemicsPositive-Strand RNA VirusesSARS-CoV-2Antiviral AgentsalphaviruscoronavirusenterovirusflavivirusRNA virusSARS-CoV-2

Identifiers

PMID36697369
PMCPMC10347887

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.