Evidence map›Paper›PMID 36697281›Full record

ArticleAmerican journal of preventive medicine2023

Associations of Adverse Childhood Experiences With Pregnancy and Infant Health.

Elizabeth A Swedo, Denise V D'Angelo, Amy M Fasula, Heather B Clayton, Katie A Ports

Registry-linked trialAbstract read
In one paragraph

Article in American journal of preventive medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06821035 (Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06821035 narecruitingnot on this mapstarted 2025, after this paper: background citation

Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences: Preventing Substance Use in Adversity- Impacted Youth

TypeinterventionalSponsorUniversity of California, IrvineRan2025 to 2028Enrolled210ConditionsAdverse Childhood Experiences, Family FunctioningArmsGarnering Resilience in Traumatized youth and families (GRIT), Digital Citizenship Curriculum (DCC)
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  8. Associations of adverse childhood experiences (ACE) with pregnancy outcomes in people with cardiac disease.European journal of obstetrics, gynecology, and reproductive biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth A SwedoFrom the Division of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address: eswedo@cdc.gov.
Denise V D'AngeloFrom the Division of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.
Amy M FasulaDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Heather B ClaytonFrom the Division of Violence Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia.
Katie A Portsand the Health Equity Research Applied, Albuquerque, New Mexico.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

introductionAdverse childhood experiences are associated with a host of negative outcomes; however, few have studied cumulative adverse childhood experiences in the context of pregnancy and infant health. This study examines state-level prevalence of adverse childhood experiences and associations with pregnancy- and infant health‒related indicators.

methodsThe study used 2016-2018 Pregnancy Risk Assessment Monitoring System population-based data from 5 states. Analyses were conducted for individual states and grouped states using similar adverse childhood experience items. Thirteen adverse childhood experience measures were included across 3 domains: abuse, neglect, and household challenges. Adverse childhood experience scores were calculated for the number of adverse childhood experiences experienced (0, 1, 2, ≥3) on the basis of available state measures. Fourteen pregnancy- and infant health‒related indicators were examined, including unwanted pregnancy, adequate prenatal care, experiences during pregnancy (e.g., smoking, abuse, depression), gestational diabetes, hypertensive disorders of pregnancy, birth outcomes (e.g., preterm birth), and breastfeeding. Adjusting for demographics, parity, health insurance status, and educational attainment, prevalence ratios and 95% CIs were calculated to examine the associations between pregnancy- and infant health‒related indicators and adverse childhood experience scores.

resultsOver 50% of respondents reported at least 1 adverse childhood experience and 13%-31% reported ≥3 adverse childhood experiences, depending on the state. Significant associations were identified in all adjusted models between adverse childhood experiences and unwanted pregnancy, smoking, physical abuse, and depression during pregnancy.

conclusionsAdverse childhood experiences are associated with risk factors that impact pregnancy and infant health. Preventing and mitigating adverse childhood experiences is an important strategy to improve pregnancy- and infant health‒related indicators.

Indexed as

Adverse Childhood ExperiencesPremature BirthChildFemaleHumansInfantInfant HealthInfant, NewbornPregnancyPrenatal CareRisk Factors

Identifiers

PMID36697281
PMCPMC10033436

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.