Evidence map›Paper›PMID 36697048›Full record

ArticleBMJ open2023

Behavioural Economics to Improve Antihypertensive Therapy Adherence (BETA): protocol for a pilot randomised controlled trial in Los Angeles.

Joseph E Ebinger, Ishita Ghai, Denisse Barajas, Rocío Vallejo, Ciantel A Blyler, Michelle Morales, Nairy Garcia, Sandy Joung, Alina Palimaru, Sebastian Linnemayr

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04029883 (Behavioral Economics to Improve Antihypertensive Therapy Adherence), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04029883 nacompletednot on this map

Behavioral Economics to Improve Antihypertensive Therapy Adherence (BETA)

TypeinterventionalSponsorCedars-Sinai Medical CenterRan2022 to 2024Enrolled60ConditionsHypertension, Medication AdherenceArmsText Message, Behavior Economic Incentive
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Joseph E EbingerSmidt Heart Institute, Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Ishita GhaiFrederick S. Pardee RAND Graduate School, RAND Corporation, Santa Monica, California, USA ighai@prgs.edu.ORCID 0000-0002-7112-257X
Denisse BarajasSmidt Heart Institute, Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Rocío VallejoSmidt Heart Institute, Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Ciantel A BlylerSmidt Heart Institute, Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Michelle MoralesSmidt Heart Institute, Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Nairy GarciaSmidt Heart Institute, Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Sandy JoungSmidt Heart Institute, Department of Cardiology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Alina PalimaruRAND Corporation, Santa Monica, California, USA.
Sebastian LinnemayrRAND Corporation, Santa Monica, California, USA.
Cedars-Sinai Medical Center · USRAND Corporation · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Barber-Pharmacist Coordination to Improve Blood Pressure Management in Black MenR01HL117983 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI ALBERT, CHRISTINE M · 2014 to 2018
$8.6M
Behavioral Economics to improve Antihypertensive Therapy Adherence (BETA)R21HL156132 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI EBINGER, JOSEPH, LINNEMAYR, SEBASTIAN · 2021 to 2022
$506k
NHLBI NIH HHS R01 HL117983NHLBI NIH HHS R21 HL156132NIH HHS P51 OD011132
6 · The paper itself

Abstract

introductionNon-adherence to antihypertensive therapy is one of the major barriers to reducing the risk of cardiovascular disease. Several interventions have targeted higher medication adherence, yet most do not result in sustained adherence. Routinisation has emerged as a potential method for mitigating this problem, but requires high motivation during the relatively long habit formation phase. This pilot randomised controlled trial aims to test the feasibility, acceptability, and preliminary efficacy of behavioural economics-based incentives and text messages to support the routinisation of the medication-taking behaviour for promoting long-term medication adherence. METHODS AND ANALYSIS: This study will recruit and randomly assign 60 adult patients seeking care for hypertension at the Cedars-Sinai Medical Center in Los Angeles to one of the three groups, ETHICS AND DISSEMINATION: The study was approved by the Cedars-Sinai Institutional Review Board (Study ID: Pro00057764). Findings will be published in scientific peer-reviewed journals. TRIAL REGISTRATION NUMBER: NCT04029883.

Indexed as

Antihypertensive AgentsEconomics, BehavioralAdultHumansLos AngelesMedication AdherencePilot ProjectsRandomized Controlled Trials as TopicAntihypertensive AgentsClinical trialsHealth economicsHypertension

Identifiers

PMID36697048
PMCPMC9884869
OpenAlexW4318170667

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.