Evidence map›Paper›PMID 36696590›Full record

ReviewAnnual review of physical chemistry2023

Studies of Local DNA Backbone Conformation and Conformational Disorder Using Site-Specific Exciton-Coupled Dimer Probe Spectroscopy.

Andrew H Marcus, Dylan Heussman, Jack Maurer, Claire S Albrecht, Patrick Herbert, Peter H von Hippel

Open access · hybridAbstract readReview
In one paragraph

Review in Annual review of physical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Studies of DNA breathing in exciton-coupled (iCy3)Proceedings of SPIE--the International Society for Optical Engineering
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrew H MarcusCenter for Optical, Molecular and Quantum Science, University of Oregon, Eugene, Oregon, USA; email: ahmarcus@uoregon.edu.
Dylan HeussmanCenter for Optical, Molecular and Quantum Science, University of Oregon, Eugene, Oregon, USA; email: ahmarcus@uoregon.edu.
Jack MaurerCenter for Optical, Molecular and Quantum Science, University of Oregon, Eugene, Oregon, USA; email: ahmarcus@uoregon.edu.
Claire S AlbrechtCenter for Optical, Molecular and Quantum Science, University of Oregon, Eugene, Oregon, USA; email: ahmarcus@uoregon.edu.
Patrick HerbertCenter for Optical, Molecular and Quantum Science, University of Oregon, Eugene, Oregon, USA; email: ahmarcus@uoregon.edu.
Peter H von HippelInstitute of Molecular Biology, University of Oregon, Eugene, Oregon, USA.
University of Oregon · US

Funding

STRUCTURE AND RELATIONS OF PROTEINS AND NUCLEIC ACIDSR01GM015792 · NIGMS · UNIVERSITY OF OREGON · PI MARCUS, ANDREW HADLEY · 1985 to 2025
$10.2M
NIGMS NIH HHS R01 GM015792
6 · The paper itself

Abstract

The processes of genome expression, regulation, and repair require direct interactions between proteins and DNA at specific sites located at and near single-stranded-double-stranded DNA (ssDNA-dsDNA) junctions. Here, we review the application of recently developed spectroscopic methods and analyses that combine linear absorbance and circular dichroism spectroscopy with nonlinear 2D fluorescence spectroscopy to study the local conformations and conformational disorder of the sugar-phosphate backbones of ssDNA-dsDNA fork constructs that have been internally labeled with exciton-coupled cyanine (iCy3)

Indexed as

DNADNA, Single-StrandedNucleic Acid ConformationPhosphatesSpectrometry, FluorescenceSugarsDNADNA, Single-StrandedPhosphatesSugars2D spectroscopyDNA breathingDNA replicationexciton-coupled dimersprotein–DNA interactionssite-specific fluorescence labeling

Identifiers

PMID36696590
PMCPMC10590263
OpenAlexW4318021324

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.