Evidence map›Paper›PMID 36696460›Full record

ArticleACS sensors2023

Handheld Purification-Free Nucleic Acid Testing Device for Point-of-Need Detection of Malaria from Whole Blood.

Aneesh Kshirsagar, Gihoon Choi, Vishaka Santosh, Tara Harvey, Robert Cory Bernhards, Weihua Guan

Open access · greenAbstract read
In one paragraph

Article in ACS sensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Saliva-STAT: Sample-to-answer saliva test for COVID-19.Sensors and actuators. B, Chemical · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aneesh KshirsagarSchool of Electrical Engineering and Computer Science, Pennsylvania State University, University Park, Pennsylvania16802, United States.ORCID 0000-0003-2288-5439
Gihoon ChoiSchool of Electrical Engineering and Computer Science, Pennsylvania State University, University Park, Pennsylvania16802, United States.
Vishaka SantoshU.S. Army, DEVCOM Chemical Biological Center, Aberdeen Proving Ground, Maryland21010, United States.
Tara HarveyU.S. Army, DEVCOM Chemical Biological Center, Aberdeen Proving Ground, Maryland21010, United States.
Robert Cory BernhardsU.S. Army, DEVCOM Chemical Biological Center, Aberdeen Proving Ground, Maryland21010, United States.
Weihua GuanSchool of Electrical Engineering and Computer Science, Pennsylvania State University, University Park, Pennsylvania16802, United States.ORCID 0000-0002-8435-9672
Pennsylvania State University · USUnited States Army Combat Capabilities Development Command · US

Funding

Home Fingerprick Blood-Based HIV Self-Test For Quantitative Monitoring Of Viral ReboundR33AI147419 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI GUAN, WEIHUA · 2023 to 2024
$1.3M
Home Fingerprick Blood-Based HIV Self-Test For Quantitative Monitoring Of Viral ReboundR61AI147419 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI GUAN, WEIHUA · 2020 to 2022
$1.0M
NIAID NIH HHS R33 AI147419NIAID NIH HHS R61 AI147419
6 · The paper itself

Abstract

World Health Organization's aim to eliminate malaria from developing/resource-limited economies requires easy access to low-cost, highly sensitive, and specific screening. We present a handheld nucleic acid testing device with on-chip automated sample preparation to detect malaria (

Indexed as

MalariaDNAHumansMicrofluidicsPlasmodium falciparumSpecimen HandlingDNAloop-mediated isothermal amplification (LAMP)malariamicrofluidicsnucleic acid testing (NAT)point-of-needpurification-free

Identifiers

PMID36696460
PMCPMC11214673
OpenAlexW4318025460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.