ArticleJournal of the American Chemical Society2023
Late-Stage C(
Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Nickel-Catalyzed Radical-Radical Cross-Coupling Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Data-Driven Approach to Understanding Tetrabutylammonium Decatungstate-Catalyzed C(spAngewandte Chemie (International ed. in English) · 2026Article
- A Dual Photoredox/Cobalt Catalytic System Enables Markovnikov-Selective Hydroaminoalkylation of Alkenes.Precision chemistry · 2026Article
- Quaternary Carbons from Amines and Acids.Journal of the American Chemical Society · 2026Article
- Formaldehyde hydrazone as a methyl reagent for nickel-catalyzed cross-coupling methylation of aryl and heteroaryl electrophiles.Nature communications · 2026Article
- Cross-ketone deacylative coupling via oxidative SNature communications · 2026Article
- Navigating the next frontier in biomedicine: breakthroughs and insights in nucleic acid therapeutics.Chemical science · 2026Review
- Development, Application, and Mechanistic Interrogation of a Dual Ni Catalysis Approach to Photoredox-Based C(spJournal of the American Chemical Society · 2025Article
- Article
- C(spAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Tetrabutylammonium decatungstate-catalyzed hydroalkylation/alkoxylation of 3-methyleneisoindolin-1-ones with alcohols/ethers through hydrogen atom transfer process.RSC advances · 2025Article
- Iron-catalyzed alkyne alkylzincation affected by counterions.Nature communications · 2025Article
- Radical Sorting Catalysis via Bimolecular Homolytic Substitution (SJournal of the American Chemical Society · 2025Review
- Late-Stage Heteroarene Alkylation via Minisci Reaction with Gaseous Alkanes Enabled by Hydrogen Atom Transfer in Flow.ACS central science · 2025Article
- Enantioselective β-C(spJournal of the American Chemical Society · 2025Article
- Visible-light-mediated site-selective C(spChemical science · 2025Article
- Synthesis of Differentially Halogenated Lissoclimide Analogues To Probe Ribosome E-Site Binding.ACS chemical biology · 2025Article
- Salen-scandium(III) complex-catalyzed asymmetric (3 + 2) annulation of aziridines and aldehydes.Beilstein journal of organic chemistry · 2025Article
- Iron-Catalyzed Cross-Electrophile Coupling for the Formation of All-Carbon Quaternary Centers.Journal of the American Chemical Society · 2024Article
- Acridine/Lewis Acid Complexes as Powerful Photocatalysts: A Combined Experimental and Mechanistic Study.ACS catalysis · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Methyl groups are well understood to play a critical role in pharmaceutical molecules, especially those bearing saturated heterocyclic cores. Accordingly, methods that install methyl groups onto complex molecules are highly coveted. Late-stage C-H functionalization is a particularly attractive approach, allowing chemists to bypass lengthy syntheses and facilitating the expedited synthesis of drug analogues. Herein, we disclose the direct introduction of methyl groups via C(
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.