Evidence map›Paper›PMID 36696075›Full record

ReviewCurrent oncology reports2023

The Microbiome's Influence on Head and Neck Cancers.

Karolina Dorobisz, Tadeusz Dorobisz, Tomasz Zatoński

Open access · hybridAbstract readReview
In one paragraph

Review in Current oncology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Karolina DorobiszDepartment of Otolaryngology, Head and Neck Surgery, Wrocław Medical University, Borowska 213, 50-556, Wrocław, Poland. dorobiszkarolina@gmail.com.ORCID 0000-0001-9369-8994
Tadeusz DorobiszDepartment of Vascular and General Surgery, Wrocław Medical University, Borowska 213, 50-556, Wrocław, Poland. tdorobisz@gmail.com.ORCID 0000-0002-9993-756X
Tomasz ZatońskiDepartment of Otolaryngology, Head and Neck Surgery, Wrocław Medical University, Borowska 213, 50-556, Wrocław, Poland. tzatonski@gmail.com.ORCID 0000-0003-3043-4806
Medical University of Silesia · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewHead and neck tumors (HNC) rank sixth among cancers worldwide. Due to their late diagnosis and poor prognosis, they are a clinical challenge. However, recent years have seen a dynamic development of science on the microbiome. The aim of the study is to discuss the role of the microbiome in HNC, the impact of the microbiome on oncogenesis, the course of the disease, as well as on treatment, and its toxicity. RECENT

findingsThe microbiome's influence on oncogenesis, the course of the disease, and the effectiveness of oncological treatment have been confirmed in cancers of the colon, pancreas, lungs, and prostate. There is no solid literature on HNC. Many studies indicate disruption of the oral microbiome and periodontal disease as potential cancer risk factors. Disruption of the microbiome increases radiotherapy's toxicity, intensifying radiation reactions. The microbiome plays an important role in cancer. It is a new target in research into new therapies. It may also be a prognostic marker of cancer development. Changes in the composition of the microbiome modulate the effectiveness of oncological treatment. More research is needed on the microbiome and its effects on HNC.

Indexed as

Head and Neck NeoplasmsMicrobiotaCarcinogenesisCell Transformation, NeoplasticHumansMaleMedical OncologyChemotherapyHead and neck cancerImmunotherapyMicrobiomeMicrobiotaOncogenesisRadiotherapyToxicity

Identifiers

PMID36696075
PMCPMC9947050
OpenAlexW4317931252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.