Evidence map›Paper›PMID 36695873›Full record

ArticleACS nano2023

Injectable Hydrogels Encapsulating Dual-Functional Au@Pt Core-Shell Nanoparticles Regulate Infarcted Microenvironments and Enhance the Therapeutic Efficacy of Stem Cells through Antioxidant and Electrical Integration.

Wei Liu, Nana Zhao, Qi Yin, Xiaoyi Zhao, Kangli Guo, Yifan Xian, Siwei Li, Chunlan Wang, Miaomiao Zhu, Yurong Du and 3 more

Open access · hybridAbstract read
In one paragraph

Article in ACS nano, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 98 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Wei LiuBeijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China.ORCID 0000-0002-3536-3915
Nana ZhaoKey Lab of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology, Ministry of Education), Beijing, 100029, China.ORCID 0000-0001-8610-3411
Qi YinBeijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China.
Xiaoyi ZhaoKey Lab of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology, Ministry of Education), Beijing, 100029, China.
Kangli GuoKey Lab of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology, Ministry of Education), Beijing, 100029, China.
Yifan XianKey Lab of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology, Ministry of Education), Beijing, 100029, China.
Siwei LiBeijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China.
Chunlan WangBeijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China.
Miaomiao ZhuBeijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China.
Yurong DuBeijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China.
Fu-Jian XuKey Lab of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology, Ministry of Education), Beijing, 100029, China.ORCID 0000-0002-1838-8811
Changyong WangBeijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China.
Jin ZhouBeijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China.ORCID 0000-0003-3128-407X
Beijing Institute of Education · CNBeijing University of Chemical Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Injectable functional biomaterials have made significant progress in cardiac regenerative. In addition, how to adjust the abominable infarction microenvironment and introduce therapeutic stem cells to improve the healing effect has become a hotspot. Herein, injectable stem cell vector is prepared by combining natural alginate hydrogel and Au@Pt nanoparticles (Au@Pt/Alg hydrogel) to encapsulate brown adipose stem cells (BASCs). Au@Pt nanoparticles with both antioxidative and conductive properties could effectively eliminate reactive oxygen species, enhance the frequency of action potential release of cardiomyocytes, and further reduce the inflammatory factors of macrophage

Indexed as

Myocardial InfarctionNanoparticlesAnimalsAntioxidantsHydrogelsMyocytes, CardiacRatsStem CellsAntioxidantsHydrogelsalginate hydrogelAu@Pt nanoparticlescardiac repairmyocardial infarctionstem cell

Identifiers

PMID36695873
PMCPMC9933615
OpenAlexW4317951865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.