Evidence map›Paper›PMID 36695870›Full record

ArticleAnalytical and bioanalytical chemistry2023

Dispersive magnetic solid-phase extraction for capsaicinoid compounds in human serum using LC-HRMS: targeted and non-targeted approaches.

María Consolación Rodríguez-Palazón, Natalia Arroyo-Manzanares, Pilar Viñas, Ignacio López-García, Manuel Hernández-Córdoba, Natalia Campillo

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

María Consolación Rodríguez-PalazónDepartment of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100, Murcia, Spain.
Natalia Arroyo-ManzanaresDepartment of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100, Murcia, Spain.
Pilar ViñasDepartment of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100, Murcia, Spain. pilarvi@um.es.ORCID http://orcid.org/0000-0001-5219-3711
Ignacio López-GarcíaDepartment of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100, Murcia, Spain.
Manuel Hernández-CórdobaDepartment of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100, Murcia, Spain.
Natalia CampilloDepartment of Analytical Chemistry, Faculty of Chemistry, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100, Murcia, Spain.
Universidad de Murcia · ES

Funding

Ministerio de Ciencia e Innovación PID2021-123201NB-I00Ministerio de Ciencia e Innovación RED2018- 102522-T
6 · The paper itself

Abstract

A new analytical method based on the use of dispersive magnetic solid-phase extraction (DMSPE) is described for the preconcentration of capsaicin (CAP), dihydrocapsaicin (DCAP), and N-vanillylnonanamide (PCAP) from human serum samples. The influence of several experimental factors affecting the adsorption (nature and amount of magnetic material, adsorption time, and pH) and desorption (nature of solvent, its volume and desorption time) steps was studied. Among seven different nanomaterials studied, the best results were obtained using magnetic multiwalled carbon nanotubes, which were characterized by means of spectrometry- and microscopy-based techniques. Analyses were performed by ultra-high-performance liquid chromatography with quadrupole-time-of-flight mass spectrometry using electrospray ionization in positive mode (UHPLC-ESI-Q-TOF-MS). The developed method was validated by obtaining several parameters, including linearity (0.3-300 μg L

Indexed as

Nanotubes, CarbonAminophenolsCapsaicinChromatography, High Pressure LiquidHumansMagnetic PhenomenaMass SpectrometrySolid Phase ExtractionVanillic Acid3,5-dichloro-1,4-aminophenolAminophenolsCapsaicindihydrocapsaicinNanotubes, CarbonVanillic Acidvanillyl-N-nonylamideCapsaicinoidsDispersive magnetic solid-phase extractionNon-targeted analysisQuadrupole-time-of-flight mass spectrometrySerumUltra-high-performance liquid chromatography

Identifiers

PMID36695870
PMCPMC10079705
OpenAlexW4318025851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.