Evidence map›Paper›PMID 36695858›Full record

Trial reportHeart and vessels2023

Feasibility of concomitant left atrial appendage closure and percutaneous coronary intervention in patients with acute coronary syndrome and atrial fibrillation: a randomized pilot study.

Denis Losik, Alexander Romanov, Igor Grazhdankin, Vitaly Shabanov, Dmitry Ponomarev, Igor Mikheenko, Ivan Peregudov, Alexey Filippenko, Nikolay Bondar, Lucas Boersma and 1 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Heart and vessels, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Practical guide on left atrial appendage closure for the non-implanting physician: an international consensus paper.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Denis LosikE. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, Novosibirsk, Russian Federation. dvlosik@gmail.com.ORCID http://orcid.org/0000-0003-4886-9648
Alexander RomanovE. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, Novosibirsk, Russian Federation.
Igor GrazhdankinE. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, Novosibirsk, Russian Federation.
Vitaly ShabanovE. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, Novosibirsk, Russian Federation.
Dmitry PonomarevE. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, Novosibirsk, Russian Federation.
Igor MikheenkoE. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, Novosibirsk, Russian Federation.
Ivan PeregudovE. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, Novosibirsk, Russian Federation.
Alexey FilippenkoE. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation, Novosibirsk, Russian Federation.
Nikolay BondarFederal Center of Cardiovascular Surgery, Khabarovsk, Russian Federation.
Lucas BoersmaDepartment of Cardiology, St Antonius Hospital Nieuwegein, Amsterdam UMC, Amsterdam, The Netherlands.
Jonathan S SteinbergCardiovascular Research Center, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Ministry of Health of the Russian Federation · RUFederal State Budgetary Institution "Federal Center For Cardiovascular Surgery" Ministry of Health of The Russian Federation · RUSt. Antonius Ziekenhuis · NLUniversity of Rochester · US

Funding

Ministry of Health of the Russian Federation 121031300225-8
6 · The paper itself

Abstract

The optimal approach for prevention of cardiovascular events and reduction of bleeding in patients with acute coronary syndrome (ACS) and atrial fibrillation (AF) is still controversial. The aim of our study is to asses our single-center experience with concomitant left atrial appendage occlusion (LAAO) and percutaneous coronary intervention (PCI). 50 patients with ACS without ST elevation and history of AF were randomized after successful PCI to LAAO or conventional medical therapy. The primary endpoints were safety and length of hospitalization. The follow-up period was 30 days. The mean procedural times were 113 ± 23 min PCI + LAAO implantation and 39 ± 19 min of PCI only (p < 0.001), while mean fluoroscopy times were 18 ± 8 min and 12 ± 8 min (p < 0.001), respectively. No procedure-related complications were observed. There was no difference observed for length of hospitalization between two groups. LAAO in patients with ACS and AF undergoing PCI appears safe.

Indexed as

Acute Coronary SyndromeAtrial AppendageAtrial FibrillationPercutaneous Coronary InterventionStrokeFeasibility StudiesHumansPilot ProjectsTreatment OutcomeAcute coronary syndromeAtrial fibrillationLeft atrial appendage occlusionPercutaneous coronary intervention

Identifiers

PMID36695858
OpenAlexW4317941452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.