Evidence map›Paper›PMID 36694954›Full record

SynthesisPharmaceutical biology2023

Efficacy and safety of

Ming Li, Yan Li, Lujing Xiang

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Pharmaceutical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ming LiDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yan LiDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Lujing XiangDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

context

objectiveTo systematically evaluate the efficacy and safety of TG combined with H1-antihistamine (H1-AH) in adults with CU.

methodsEligible randomized controlled trials were searched in eight databases until May 31, 2022, including CNKI, WanFang, VIP, SinoMed, PubMed, Cochrane Library, Embase, and Web of Science. The search terms included urticaria,

resultsA total of 27 studies with 2788 patients were included. The pooled results showed that TG plus H1-AH was superior to H1-AH alone in cure rate (RR = 1.37, 95% CI = 1.15 to 1.63,

conclusionsThe combination of TG and H1-AH is a promising and safe treatment for adults with refractory CU. Further high-quality studies are needed to confirm the evidence.

Indexed as

Chronic UrticariaDrugs, Chinese HerbalAdultGlycosidesHumansMedicine, Chinese TraditionalTripterygiumDrugs, Chinese HerbalGlycosidesadverse eventeffectivenessRandomized controlled trialstraditional Chinese medicine

Identifiers

PMID36694954
PMCPMC9879204
OpenAlexW4317914521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.