Evidence map›Paper›PMID 36694912›Full record

ArticleBioengineered2022

Geniposide promotes splenic Treg differentiation to alleviate colonic inflammation and intestinal barrier injury in ulcerative colitis mice.

Yun Yu, Yong Bian, Jian-Xin Shi, Yu Gu, Dong-Ping Yuan, Bin Yu, Le Shi, Da-Hai Dou

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yun YuSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Yong BianLaboratory Animal Center, Nanjing University of Chinese Medicine, Nanjing, China.
Jian-Xin ShiAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Yu GuSchool of Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Dong-Ping YuanSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Bin YuSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Le ShiSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Da-Hai DouDepartment of Pharmacy, Jiangsu Province Hospital, Nanjing, China.
Nanjing University of Chinese Medicine · CNJiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Geniposide has been proven to have a therapeutic effect on ulcerative colitis (UC) in animals, but its potential mechanism in UC remains to be clarified. The purpose of this study was to confirm the efficacy of geniposide in UC and to investigate the possible mechanism of geniposide in UC treatment.

Indexed as

Colitis, UlcerativeAnimalsCaco-2 CellsCell DifferentiationDisease Models, AnimalForkhead Transcription FactorsHumansInflammationIridoidsLipopolysaccharidesMiceMice, Inbred C57BLSpleenT-Lymphocytes, RegulatoryTumor Necrosis Factor-alphaForkhead Transcription FactorsgeniposideIridoidsLipopolysaccharidesTumor Necrosis Factor-alphaGeniposideimmunityinflammationspleenTregulcerative colitis

Identifiers

PMID36694912
PMCPMC9995132
OpenAlexW4318026050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.