Evidence map›Paper›PMID 36694608›Full record

ArticleOxford medical case reports2023

Cerebral venous sinus thrombosis after COVID-19 vaccination: a case report and literature review.

Mohamed Elfil, Mohammad Aladawi, Dmitry Balian, Ismail Fahad, Daniel J Zhou, Brian Villafuerte-Trisolini, Thomas Scott Diesing

Open access · goldAbstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Post-COVID-19 Vaccination CNS Magnetic Resonance Imaging Findings: A Systematic Review.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mohamed ElfilDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA.ORCID https://orcid.org/0000-0002-1125-2946
Mohammad AladawiDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA.
Dmitry BalianDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA.
Ismail FahadDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA.
Daniel J ZhouDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA.
Brian Villafuerte-TrisoliniDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA.
Thomas Scott DiesingDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA.
University of Nebraska Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As COVID-19 vaccines became widely available, there have been reports of neurovascular complications. In this article, we aim to report a case of cerebral venous sinus thrombosis (CVST) induced by COVID-19 vaccination, with a literature review on similar cases as well as the potential pathophysiological mechanisms. Our case is a healthy male who developed headache, vomiting, photophobia and diplopia after receiving the Ad26.COV2.S vaccine. Fundus examination showed papilledema, and magnetic resonance imaging of the brain and cerebral veins showed CVST involving the superior sagittal sinus and right transverse sinus extending into the right jugular vein. Hypercoagulability workup was unremarkable, and the patient received immunotherapy and anticoagulation. Following this treatment, symptoms resolved, and he had no residual neurologic deficits. Developing neurologic manifestations, especially severe headaches with papilledema, after COVID-19 vaccination should warrant neuroimaging. Early recognition and management of CVST are essential for good clinical outcomes.

Identifiers

PMID36694608
PMCPMC9853928
OpenAlexW4317538694

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.