Evidence map›Paper›PMID 36694505›Full record

ArticleCureus2022

Life-Threatening Hypotension in a Brain-Injured, Multi-Trauma Patient With Unilateral Adrenal Gland Damage: How a Single Hydrocortisone Dose Revealed Relative Corticosteroid Insufficiency.

Georgios E Zakynthinos, Paris Zygoulis, Alexandra Tsikrika, Vasiliki Tsolaki

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Georgios E ZakynthinosCardiology, 3rd Department of Cardiology, Athens Chest Disease Hospital "Sotiria", Athens, GRC.
Paris ZygoulisCritical Care, University Hospital of Larissa, University of Thessaly, Faculty of Medicine, Larissa, GRC.
Alexandra TsikrikaRadiology, University Hospital of Larissa, University of Thessaly, Faculty of Medicine, Larissa, GRC.
Vasiliki TsolakiCritical Care, University Hospital of Larissa, University of Thessaly, Faculty of Medicine, Larissa, GRC.
University Hospital of Larissa · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a multi-trauma, brain-injured young patient with unilateral adrenal gland injury presenting with refractory shock. Acute adrenal insufficiency was revealed after an abrupt hemodynamic response to a corticosteroid; the resistant shock was quickly resolved with IV hydrocortisone. Although available data do not support the use of empiric steroids in trauma patients (with or without brain injury), this case demonstrates that adrenal insufficiency must be considered in the differential diagnosis when shock exists; adrenal gland injury, even unilateral, may play an additional factor. In these cases, an urgent decision is required in order to influence the outcome.

Indexed as

adrenal gland injuryadrenal insufficiency (ai)corticosteroidsintensive careresistant shock

Identifiers

PMID36694505
PMCPMC9867564
OpenAlexW4312185112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.