Evidence map›Paper›PMID 36694238›Full record

Observational studyCritical care (London, England)2023

Pattern of disease and determinants of mortality among ICU patients on mechanical ventilator in Sub-Saharan Africa: a multilevel analysis.

Semagn Mekonnen Abate, Bivash Basu, Bedru Jemal, Siraj Ahmed, Bahru Mantefardo, Tagesse Taye

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Critical care (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05303831 (Pattern of Disease and Determinants of Clinical Outcomes Among ICU Patients on Mechanical Ventilator in Southern Ethiopia), which is not on this map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05303831 completednot on this map

Pattern of Disease and Determinants of Clinical Outcomes Among ICU Patients on Mechanical Ventilator in Southern Ethiopia: A Multi-center Prospective Cohort Study

Typeobservational_patient_registrySponsorDilla UniversityRan2022 to 2022Enrolled630ConditionsClinical OutcomesArmsMechanical ventilator
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Semagn Mekonnen AbateDepartment of Anesthesiology, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia. semmek17@gmail.com.
Bivash BasuDepartment of Anesthesiology, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia.
Bedru JemalDepartment of Anesthesiology, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia.
Siraj AhmedDepartment of Anesthesiology, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia.
Bahru MantefardoDepartemnt of Internal Medicine, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia.
Tagesse TayeDepartment of Anesthesiology, College of Health Sciences and Medicine, Hawassa University, Hawassa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe global mortality rate of patients with MV is very high, despite a significant variation worldwide. Previous studies conducted in Sub-Saharan Africa among ICU patients focused on the pattern of admission and the incidence of mortality. However, the body of evidence on the clinical outcomes among patients with MV is still uncertain.

objectiveThe objective of this study was to investigate the pattern of disease and determinants of mortality among patients receiving mechanical ventilation in Southern Ethiopia.

methodsSix hundred and thirty patients on mechanical ventilation were followed for 28 days, and multilevel analysis was used to account for the clustering effect of ICU care in the region.

resultsThe incidence of 28-day mortality among patients with MV was 49% (95% CI: 36-58). The multilevel multivariate analysis revealed that being diabetic, having GSC < 8, and night time admission (AOR = 7.4; 95% CI: 2.96-18.38), (AOR = 5.9; (5% CI: 3.23, 10.69), and (AOR = 2.5; 95% CI: 1.24, 5.05) were predictors.

conclusionThe higher 28-day mortality among ICU patients on mechanical ventilation in our study might be attributed to factors such as delayed patient presentation, lack of resources, insufficient healthcare infrastructure, lack of trained staff, and financial constraints.

trial registrationThe protocol was registered retrospectively on ( NCT05303831 ).

Indexed as

Intensive Care UnitsRespiration, ArtificialAfrica South of the SaharaHospital MortalityHumansMultilevel AnalysisRetrospective StudiesVentilators, Mechanical

Identifiers

PMID36694238
PMCPMC9875485

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.