Evidence map›Paper›PMID 36694232›Full record

ArticleJournal of pharmaceutical policy and practice2023

Clinical pharmacists' intervention on pain management in cancer patients (PharmaCAP trial): study protocol for a randomized controlled trial.

Sunil Shrestha, Ali Qais Blebil, Siew Li Teoh, Simit Sapkota, Bhuvan Kc, Vibhu Paudyal, Siew Hua Gan

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of pharmaceutical policy and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05021393 (Impact of Clinical Pharmacist Intervention as a Part of the Multidisciplinary Team on Clinical Outcomes in Cancer Patients With Pain in Nepal), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05021393 nacompletednot on this map

Impact of Clinical Pharmacist Intervention as a Part of the Multidisciplinary Team on Clinical Outcomes in Cancer Patients With Pain in Nepal: A Feasibility Pilot Randomized Controlled Trial (PharmCaP Trial)

TypeinterventionalSponsorMonash University MalaysiaRan2022 to 2023Enrolled92ConditionsCancer, Cancer PainArmsClinical Pharmacist Intervention
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Clinical pharmacist interventions on pain management in cancer patients (PharmaCAP) in low resource settings: a multicenter feasibility-pilot randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  3. Article
  4. Examining clinical pharmacist interventions and identifying opioid medication-related issues in patients with cancer.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2025
    Observational
  5. Article
  6. Article
  7. Current practices, gaps, and opportunities on the role of clinical pharmacists in cancer pain management: Perspectives from Nepal.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2023
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Sunil ShresthaSchool of Pharmacy, Monash University Malaysia, 47500, Subang Jaya, Selangor, Malaysia. Sunil.Shrestha@monash.edu.ORCID http://orcid.org/0000-0002-9174-7120
Ali Qais BlebilSchool of Pharmacy, Monash University Malaysia, 47500, Subang Jaya, Selangor, Malaysia. aliblebil@yahoo.com.ORCID http://orcid.org/0000-0002-7480-1260
Siew Li TeohSchool of Pharmacy, Monash University Malaysia, 47500, Subang Jaya, Selangor, Malaysia.ORCID http://orcid.org/0000-0003-4163-7895
Simit SapkotaDepartment of Clinical Oncology, Kathmandu Cancer Center, Tathali, Bhaktapur, Bagmati Province, Nepal.ORCID http://orcid.org/0000-0002-6290-4318
Bhuvan KcSchool of Pharmacy, Monash University Malaysia, 47500, Subang Jaya, Selangor, Malaysia.ORCID http://orcid.org/0000-0002-9135-962X
Vibhu PaudyalSchool of Pharmacy, College of Medical and Dental Sciences, Sir Robert Aitken Institute for Medical Research, University of Birmingham Edgbaston, Birmingham, B15 2TT, UK.ORCID http://orcid.org/0000-0002-4173-6490
Siew Hua GanSchool of Pharmacy, Monash University Malaysia, 47500, Subang Jaya, Selangor, Malaysia.ORCID http://orcid.org/0000-0001-6470-3651
Monash University Malaysia · MYBhaktapur Cancer Hospital · NPUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEvidence-based services to support cancer patients with pain via clinical pharmacy services are currently lacking. Therefore, there is a need to undertake a randomized controlled trial (RCT) to explore the effectiveness of clinical pharmacists (CPs)' input into the multidisciplinary team (MDT) in providing better therapeutic outcomes for cancer pain management.

objectivesThe main aim of this pilot RCT is to determine the feasibility and preliminary efficacy of integrating CPs into the MDT for cancer pain management on the clinical outcomes of cancer patients experiencing pain.

methodsThis study protocol outlines two-armed multicenter pilot RCT. Cancer patients suffering from pain will be randomly allocated to receive either clinical pharmacy services, i.e., PharmaCAP trial intervention from the CP, or the usual standard care (i.e., control group). Patients will be recruited consecutively from two hospitals in Kathmandu valley, Nepal. The outcomes will be assessed at baseline (pre-intervention) and 4 weeks post-intervention. The primary feasibility outcomes will include eligibility rate, recruitment rate, willingness to participate, acceptability of screening procedures and random allocation, possible contamination between the groups, intervention fidelity and compliance, treatment satisfaction, and patient understanding of the provided interventions. Subsequently, the primary clinical outcome, i.e., pain intensity of cancer patients, will be assessed. The secondary clinical outcomes will include health-related quality of life (HRQoL), anxiety, depression, adverse drug reactions, and patient medication compliance following the integration of CP into the healthcare team. DISCUSSION: The feasibility and potential for integrating CP involvement in MDT to improve clinical outcomes of cancer patients with pain will be evaluated through the PharmaCAP trial.

trial registrationClinicalTrials.gov NCT05021393. Registered on 25th August 2022.

Indexed as

Cancer painCancer patientsClinical pharmacistFeasibility studyPilot trialRandomized controlled trial

Identifiers

PMID36694232
PMCPMC9875431
OpenAlexW4317894204

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.