Evidence map›Paper›PMID 36694146›Full record

ArticleBMC pulmonary medicine2023

Health-related quality of life decreases in young people with asthma during the transition from adolescence to young adulthood: a birth cohort study.

Maria Ödling, Niklas Andersson, Christer Janson, Erik Melén, Anna Bergström, Inger Kull

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Asthma increases short-time sickness absence and presenteeism in young adults.The journal of allergy and clinical immunology. Global · 2025
    Article
  4. COVID-19 vaccine uptake among young adults: Influence of asthma and sociodemographic factors.The journal of allergy and clinical immunology. Global · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maria ÖdlingDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden. Maria.Odling@ki.se.
Niklas AnderssonInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Christer JansonDepartment of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
Erik MelénDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Anna BergströmInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Inger KullDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SEUppsala University · SE

Funding

European Research Council TRIBAL, 757919Forskningsrådet om Hälsa, Arbetsliv och Välfärd 2017-00526Svenska Forskningsrådet Formas 2016-01646Vetenskapsrådet 2016-03086Vetenskapsrådet 2018-02524Vetenskapsrådet 2020-02170
6 · The paper itself

Abstract

backgroundDuring the transition from paediatric to adult healthcare there is a gap between asthma guidelines and actual management with decreased healthcare consultations and dispensations of asthma medications after the transition to adult healthcare among young people with asthma. How health-related quality of life (HRQoL) develops during the transition from adolescence to young adulthood is unclear. Our aim was therefore to investigate HRQoL among young people with asthma during the transition to adulthood. Further, to assess if level of asthma control and physical activity influence any potential association between asthma and HRQoL.

methodsThe study population consisted of 2268 participants from the ongoing Swedish population-based prospective birth cohort BAMSE (Barn/Child, Allergy, Milieu, Stockholm, Epidemiology). HRQoL was measured using the instrument EQ-5D-3 L and three general questions. The EQ-5D-3 L consists of the EQ-5D descriptive system and the EQ visual analogue scale (EQ VAS). The EQ-5D-3 L instrument and questions on general health, symptoms and treatment of asthma, and lifestyle factors were based on data from follow-ups at 16 and 24 years. Cross-sectional analyses were made.

resultsAt the 24-year follow-up, the adjusted median values of EQ VAS were lower compared with at the 16-year follow-up; among both participants with asthma (80 vs. 85, p < 0.01) and those without asthma (80 vs. 87, p < 0.01). At the 24-year follow-up, participants with uncontrolled asthma had a lower adjusted median EQ VAS score than peers with controlled/partly controlled asthma (75 vs. 80, p = 0.03). Further, young adults with asthma who did not fulfil the WHO recommendations on physical activity had lower EQ VAS scores than peers who did (70 vs. 80, p < 0.01).

conclusionHRQoL is lower in young adulthood than in adolescence. Young adults with asthma having uncontrolled disease or who are physically inactive appear to be particularly vulnerable.

Indexed as

AsthmaQuality of LifeAdolescentAdultChildCohort StudiesCross-Sectional StudiesHealth StatusHumansProspective StudiesSurveys and QuestionnairesYoung AdultAsthma controlBirth cohortGeneral healthPhenotypePhysical activityWell-being

Identifiers

PMID36694146
PMCPMC9872377
OpenAlexW4317830815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.