Evidence map›Paper›PMID 36694123›Full record

ArticleBMC nephrology2023

COVID-19 associated acute transplant failure after AB0-incompatible living donor kidney transplantation - a case report.

Kristina Boss, Margarethe Konik, Jan Hinrich Bräsen, Jessica Schmitz, Christiane Jürgens, Andreas Kribben, Oliver Witzke, Sebastian Dolff, Anja Gäckler

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Kidney involvement and anemia in COVID-19 infection.World journal of nephrology · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kristina BossDepartment of Nephrology, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany. kristina.boss@uk-essen.de.
Margarethe KonikDepartment of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Jan Hinrich BräsenNephropathology Unit, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Jessica SchmitzNephropathology Unit, Institute of Pathology, Hannover Medical School, Hannover, Germany.
Christiane JürgensDepartment of Nephrology, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany.
Andreas KribbenDepartment of Nephrology, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany.
Oliver WitzkeDepartment of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Sebastian DolffDepartment of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Anja GäcklerDepartment of Nephrology, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany.
University of Duisburg-Essen · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionImmunosuppressive therapy is associated with an increased risk of severe courses of SARS-CoV-2 infection, with frequently delayed viral clearance. We report a case of an acute kidney transplant failure in persistent SARS-CoV-2 infection in a patient with absolute B-cell depletion after administration of rituximab for AB0-incompatible living donor kidney transplantation. CASE PRESENTATION: A 34-year-old unvaccinated patient is diagnosed with SARS-CoV-2 infection four months after kidney transplantation. With only mild symptoms and an estimated glomerular filtration rate (eGFR) of 44 ml/min/1.73 m

conclusionLack of viral clearance can lead to complications of SARS-CoV-2 infection with atypical manifestations. In kidney transplant patients, before initiating therapy, the differential diagnoses of "rejection" and "virus infection" should be weighed against each other in an interdisciplinary team of nephrologists, infectious diseases specialists and pathologists.

Indexed as

COVID-19Kidney DiseasesKidney TransplantationGraft RejectionHumansImmunoglobulin GIn Situ Hybridization, FluorescenceLiving DonorsSARS-CoV-2Immunoglobulin GAB0-incompatibleCase reportCOVID-19Kidney transplantationRejection

Identifiers

PMID36694123
PMCPMC9873206
OpenAlexW4317898397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.