Evidence map›Paper›PMID 36694087›Full record

ArticleChild psychiatry and human development2024

Age-Related Variations of Genetic and Environmental Contributions to the Covariation of Fear, Distress and Externalizing Symptoms: A Twin Study in Childhood and Adolescence.

Stefano De Francesco, Simona Scaini, Guido Alessandri, Emanuela Medda, Laura Camoni, Maria Antonietta Stazi, Corrado Fagnani

Abstract readTwin Study
In one paragraph

Article in Child psychiatry and human development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Stefano De FrancescoChild and Youth Lab, Sigmund Freud University, Milan, Italy.
Simona ScainiChild and Youth Lab, Sigmund Freud University, Milan, Italy.
Guido AlessandriDepartment of Psychology, University of Rome "Sapienza", Via Dei Marsi 78, 00185, Rome, Italy. guido.alessandri@uniroma1.it.
Emanuela MeddaCentre for Behavioural Sciences and Mental Health, Istituto Superiore Di Sanità, Rome, Italy.
Laura CamoniCentre for Behavioural Sciences and Mental Health, Istituto Superiore Di Sanità, Rome, Italy.
Maria Antonietta StaziCentre for Behavioural Sciences and Mental Health, Istituto Superiore Di Sanità, Rome, Italy.
Corrado FagnaniCentre for Behavioural Sciences and Mental Health, Istituto Superiore Di Sanità, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The frequency with which Internalizing and Externalizing symptoms co-occur suggests that, behind both domains, there may be a common susceptibility represented by a general psychopathology factor. However, it's still unclear whether this common susceptibility is affected by age-related variations. Internalizing (i.e., Fear and Distress) and Externalizing symptoms were evaluated in 803 twin pairs from the population-based Italian Twin Registry. Model-fitting analysis was performed separately in the 6-14 and 15-18 age groups to estimate genetic and environmental contributions to the covariance among symptoms. For the 6-14 group, a multivariate Cholesky model best fitted the data, while, for the 15-18 group, the best fit was provided by a Common Pathway model in which nearly 50% of total variance of each trait was mediated by common genetic factors. Our findings support a common susceptibility behind Internalizing and Externalizing symptoms, mainly genetic in origin, that becomes more evident at the beginning of puberty.

Indexed as

FearAdolescentAge FactorsChildFemaleGene-Environment InteractionHumansItalyMalePsychological DistressRegistriesChildren and adolescentsInternalization externalizationLatent susceptibility factorTwin study

Identifiers

PMID36694087
PMCPMC11362379

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