Evidence map›Paper›PMID 36694083›Full record

Observational studyReproductive sciences (Thousand Oaks, Calif.)2023

IVF/ICSI Outcomes After a Freeze-All Strategy: an Observational Cohort Study.

Mathilde Bourdon, Asim Alwohaibi, Chloé Maignien, Louis Marcellin, Ahmed Chargui, Khaled Pocate Cheriet, Catherine Patrat, Charles Chapron, Pietro Santulli

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Reproductive sciences (Thousand Oaks, Calif.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mathilde BourdonFaculté de Santé, Faculté de Médecine Paris Centre, Université de Paris, Paris, France.
Asim AlwohaibiFaculté de Santé, Faculté de Médecine Paris Centre, Université de Paris, Paris, France.
Chloé MaignienFaculté de Santé, Faculté de Médecine Paris Centre, Université de Paris, Paris, France.
Louis MarcellinFaculté de Santé, Faculté de Médecine Paris Centre, Université de Paris, Paris, France.
Ahmed CharguiFaculté de Santé, Faculté de Médecine Paris Centre, Université de Paris, Paris, France.
Khaled Pocate CherietFaculté de Santé, Faculté de Médecine Paris Centre, Université de Paris, Paris, France.
Catherine PatratFaculté de Santé, Faculté de Médecine Paris Centre, Université de Paris, Paris, France.
Charles ChapronFaculté de Santé, Faculté de Médecine Paris Centre, Université de Paris, Paris, France.
Pietro SantulliFaculté de Santé, Faculté de Médecine Paris Centre, Université de Paris, Paris, France. pietro.santulli@aphp.fr.ORCID 0000-0002-4985-7326
Université Paris Cité · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to inform patients undergoing ART regarding their chances for motherhood, it seems useful to describe "freeze all" outcomes according to the different potential indications. The goal of this study was to examine the impact of a "freeze-all approach" on the cumulative live birth rate (cLBR) according to the indication. It is a cohort study including women who had undergone ovarian stimulation (OS) using an antagonist protocol with GnRH agonist triggering between 09.2016 and 09.2018 followed by a freeze-all cycle of blastocyst embryos. The ART outcomes were compared between the two main indications of the freeze-all strategy which were in our cohort: risk of ovarian hyperstimulation syndrome (OHSS) and endometriosis. The ART outcomes were also described for the others indications (inadequate endometrium and/or premature progesterone elevation at trigger day, two or more previous ART failures, and autoimmune disease and/or a high risk of thromboembolic disease (AI and/or TE risk)). In total, 658 women were included. The cLBR in the total population was 37.7% (248/658). The cLBR was significantly higher in the "OHSS risk" group (133/281, 47.3%) than in the "endometriosis" group (69/190, 36.3%) (p = 0.017). No significant differences were noted regarding perinatal outcomes, except a significantly higher risk of placenta praevia (PP) observed in the "endometriosis" group (10.1%) (p = 0.002). The "freeze-all approach" yielded good results in terms of the cLBR and especially in case of OHSS risk. These data should be taken into account when informing patients about the ART strategy and their chances of motherhood.

Indexed as

Fertilization in VitroOvarian Hyperstimulation SyndromeCohort StudiesFemaleGonadotropin-Releasing HormoneHumansOvulation InductionPregnancyPregnancy RateRetrospective StudiesSperm Injections, IntracytoplasmicGonadotropin-Releasing HormoneCryopreseservationEmbryo transferEndometriosisIn vitro fertilizationOvarian hyperstimulation syndrome

Identifiers

PMID36694083
OpenAlexW4317879249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.