Evidence map›Paper›PMID 36693882›Full record

ArticleScientific reports2023

Geography shapes the genomics and antimicrobial resistance of Salmonella enterica Serovar Enteritidis isolated from humans.

Guojie Cao, Shaohua Zhao, Dai Kuang, Chih-Hao Hsu, Lanlan Yin, Yan Luo, Zhao Chen, Xuebin Xu, Errol Strain, Patrick McDermott and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Genetic and Phenotypic Characterization of aAntibiotics (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Phylodynamic analysis ofMicrobial genomics · 2026
    Article
  7. Review
  8. Seven Years ofMicroorganisms · 2025
    Article
  9. Article
  10. Review
  11. Molecular epidemiology ofAntimicrobial agents and chemotherapy · 2025
    Article
  12. Genomic epidemiology ofMicrobial genomics · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. PipC affects the virulence ofFrontiers in microbiology · 2025
    Article
  17. Article
  18. Molecular Characteristics of Epidemiologically SuccessfulTransboundary and emerging diseases · 2025
    Article
  19. Emerging Strategies against Non-TyphoidalCurrent issues in molecular biology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Guojie CaoCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD, 20740, USA. Guojie.Cao@fda.hhs.gov.
Shaohua ZhaoCenter for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD, 20708, USA.
Dai KuangRuijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chih-Hao HsuCenter for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD, 20708, USA.
Lanlan YinCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD, 20740, USA.
Yan LuoCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD, 20740, USA.
Zhao ChenJoint Institute for Food Safety and Applied Nutrition, Center for Food Safety & Security Systems, Department of Nutrition and Food Science, University of Maryland, College Park, MD, USA.
Xuebin XuShanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Errol StrainCenter for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD, 20708, USA.
Patrick McDermottCenter for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD, 20708, USA.
Marc AllardCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD, 20740, USA.
Eric BrownCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD, 20740, USA.
Jianghong MengJoint Institute for Food Safety and Applied Nutrition, Center for Food Safety & Security Systems, Department of Nutrition and Food Science, University of Maryland, College Park, MD, USA.
Jie ZhengCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD, 20740, USA. Jie.Zheng@fda.hhs.gov.

Funding

Cooperative Agreement to Support the Joint Institute for Food Safety and Applied Nutrition (JIFSAN)U01FD001418 · FDA · UNIV OF MARYLAND, COLLEGE PARK · PI Jianghong Meng · 2005 to 2026
$55.4M
FDA HHS U01 FD001418
6 · The paper itself

Abstract

Multidrug-resistant (MDR) Salmonella has been a long-standing challenge in public health and food safety. The prevalence of MDR S. Enteritidis, especially isolated from humans, in China is significantly higher than those from the U.S. and other countries. A dataset of 197 S. Enteritidis genomes, including 16 sequenced clinical isolates from China and 181 downloaded genomes of human isolates from the U.S., Europe, and Africa, was analyzed for genomic diversity, virulence potential, and antimicrobial resistance (AMR). Phylogenomic analyses identified four major well-supported clades (I-IV). While AMR genotype in the majority of isolates in clades I and IV displayed as pan-susceptible, 81.8% (9/11) and 22.4% (13/58) of isolates in clades III and II were MDR, respectively. It is noted that 77% (10/13) of MDR isolates in clade II were from China. The most common antimicrobial resistance genes (ARGs) carried by the Chinese isolates were aph(3')-IIa, bla

Indexed as

Salmonella entericaSalmonella enteritidisAnti-Bacterial AgentsDrug Resistance, BacterialDrug Resistance, Multiple, BacterialGenomicsGeographyHumansMicrobial Sensitivity TestsPhylogenyAnti-Bacterial Agents

Identifiers

PMID36693882
PMCPMC9873609

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.