ArticleNature communications2023
A natural biological adhesive from snail mucus for wound repair.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
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Who cites it
82 citing papers in PubMed.
- Hydrogel-Based intraperitoneal drug delivery platforms for peritoneal metastasis: strategies, advances, and prospects.Drug delivery · 2026Review
- Recent Advances in Biomimetic Hydrogels for Bioelectronics and Human-Machine Interactions.Gels (Basel, Switzerland) · 2026Review
- LiposomalInternational journal of molecular sciences · 2026Article
- Reversible, Chemically Triggered Water Retention in Disulfide Cross-Linked Synthetic Conserved Anterior Mucus Proteins (SCAMPs).Macromolecules · 2026Article
- Healing the Sole: Combining Natural Plant Extracts and Conventional Drugs in Wound Delivery Systems for Diabetic Foot Ulcer Treatment.International journal of molecular sciences · 2026Review
- Lattice-Electron Synergistic Pinning Strategy for Intensified Regeneration of Spent Ternary Cathodes.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Ambient Light-Activatable Luminescent Particle-Embedded Conformal Patch for Photochemical Tissue Bonding and Photobiomodulated Healing.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Integrating in vivo and in silico: a comprehensive study of Helix aspersa mucin's therapeutic properties.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Shelf-Stable, Rapid-Gelling, and Robust Thrombin-Independent Fibrinogen-Based Hydrogels for Massive Hemorrhage Control.Advanced healthcare materials · 2026Article
- Strong Adhesives Mediated by Dynamic Phase-Locking.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Effectiveness of a heparin-like glycosaminoglycan from snail mucus in a murine model of dry eye.Journal of translational medicine · 2026Article
- Bio-Based Microfluidics With Snail Slime: A By-Product of Agriculture Plays an Exciting Role in the Chemistry of Microfluidic Reaction Chambers.Macromolecular rapid communications · 2026Article
- Seta-Inspired Mechano-Intelligent Janus Bandage with Coordinated Adhesion-Contraction for Minimizing Scarring.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Mucin-Based Biomimetic Patches for Dynamic Heart Repair: Auxetic Structures and Translational Challenges.Cardiovascular engineering and technology · 2026Review
- In-situ fabrication of a soluble PVP/ snail mucus-based fibrous facial mask via handheld electrospinning.Scientific reports · 2026Article
- Vibrio choleraeadhesin-derived peptides mediate strong pull-off forces in aqueous media with high ionic strength.Colloids and surfaces. B, Biointerfaces · 2026Article
- Immunomodulatory hydrogel reprograms IL-17/NF-κB signaling to drive regeneration in diabetic wounds.Materials today. Bio · 2026Article
- The Self-amplifying Inflammatory Cascade in Obstetric Antiphospholipid Syndrome: From Pathophysiology to Placenta-centric Immunotherapeutic Targets.Clinical reviews in allergy & immunology · 2026Review
- Dynamic glycan network engineering of native mucin enables reversible, self-healing, and adhesive hydrogel interfaces.Nanoscale advances · 2026Article
- Insights Into Macrophage Polarization and M1/M2 Balance in Diabetic Foot Ulcers.Journal of diabetes · 2026Review
22 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The discovery of natural adhesion phenomena and mechanisms has advanced the development of a new generation of tissue adhesives in recent decades. In this study, we develop a natural biological adhesive from snail mucus gel, which consists a network of positively charged protein and polyanionic glycosaminoglycan. The malleable bulk adhesive matrix can adhere to wet tissue through multiple interactions. The biomaterial exhibits excellent haemostatic activity, biocompatibility and biodegradability, and it is effective in accelerating the healing of full-thickness skin wounds in both normal and diabetic male rats. Further mechanistic study shows it effectively promotes the polarization of macrophages towards the anti-inflammatory phenotype, alleviates inflammation in chronic wounds, and significantly improves epithelial regeneration and angiogenesis. Its abundant heparin-like glycosaminoglycan component is the main active ingredient. These findings provide theoretical and material insights into bio-inspired tissue adhesives and bioengineered scaffold designs.
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