Evidence map›Paper›PMID 36693630›Full record

ArticleEnvironmental science & technology2023

Replacement Flame-Retardant 2-Ethylhexyldiphenyl Phosphate (EHDPP) Disrupts Hepatic Lipidome: Evidence from Human 3D Hepatospheroid Cell Culture.

Chander K Negi, Darshak Gadara, Jiri Kohoutek, Lola Bajard, Zdeněk Spáčil, Ludek Blaha

Abstract read
In one paragraph

Article in Environmental science & technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. A targeted lipidomics workflow for high-throughput phenotyping and mechanism-based in vitro hepatotoxicity studies.Toxicology in vitro : an international journal published in association with BIBRA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chander K NegiRECETOX, Faculty of Science, Masaryk University, Kotlarska 2, 61137 Brno, Czech Republic.ORCID 0000-0002-1568-3962
Darshak GadaraRECETOX, Faculty of Science, Masaryk University, Kotlarska 2, 61137 Brno, Czech Republic.ORCID 0000-0002-3141-8990
Jiri KohoutekRECETOX, Faculty of Science, Masaryk University, Kotlarska 2, 61137 Brno, Czech Republic.
Lola BajardRECETOX, Faculty of Science, Masaryk University, Kotlarska 2, 61137 Brno, Czech Republic.
Zdeněk SpáčilRECETOX, Faculty of Science, Masaryk University, Kotlarska 2, 61137 Brno, Czech Republic.ORCID 0000-0002-7505-4332
Ludek BlahaRECETOX, Faculty of Science, Masaryk University, Kotlarska 2, 61137 Brno, Czech Republic.ORCID 0000-0002-7314-7455

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aims to evaluate the effects of repeated exposure to 2-ethylhexyldiphenyl phosphate (EHDPP) on human liver cells.

Indexed as

Flame RetardantsPhosphatesCell Culture TechniquesHumansLipidomicsLipidsLiverFlame RetardantsLipidsPhosphates3D spheroidsflame retardantslipidomicsmetabolic disrupting chemicalsrepeat dose toxicity

Identifiers

PMID36693630
PMCPMC9910051

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.