Unintended consequences: Renaming botulinum neurotoxin-producing species of clostridium and related species.

Carolina Lúquez, Jessica L Halpin, Janet Dykes

Open access · hybridAbstract readReview

In one paragraph

Review in Toxicon : official journal of the International Society on Toxinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.6field-weighted citation impact, top 32% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

Isolation and Characterization of Botulinum Neurotoxin-ProducingChina CDC weekly · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Carolina LúquezCenters for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: CLuquez@cdc.gov.

Jessica L HalpinCenters for Disease Control and Prevention, Atlanta, GA, USA.

Janet DykesCenters for Disease Control and Prevention, Atlanta, GA, USA.

Centers for Disease Control and Prevention · US

Funding

Intramural CDC HHS CC999999

6 · The paper itself

Abstract

Botulinum neurotoxin-producing species of Clostridium are highly diverse. Clostridium botulinum could represent at least four different species of Clostridium. In addition, strains that do not produce botulinum neurotoxin are closely related to toxigenic strains, probably representing the same species. Although reclassification of these organisms has been proposed in the past, their species names have remained unchanged, mainly because of the premise that changing names of medically relevant organisms might cause confusion in the healthcare and scientific community. In this review, we discuss the possible unintended consequences of reclassifying botulinum neurotoxin-producing species of Clostridium, which are of public health, medical, and biodefense interest.

Indexed as

Botulinum ToxinsClostridium botulinumClostridiumBotulinum ToxinsBotulinum neurotoxinBotulinum neurotoxin-producing clostridiaClostridium botulinumTaxonomy

Identifiers

PMID36693544

DOI10.1016/j.toxicon.2023.107036

PMCPMC10866187

OpenAlexW4317677645

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.