Evidence map›Paper›PMID 36693530›Full record

ReviewExperimental gerontology2023

Age-related changes in gait biomechanics and their impact on the metabolic cost of walking: Report from a National Institute on Aging workshop.

Katherine A Boyer, Kate L Hayes, Brian R Umberger, Peter Gabriel Adamczyk, Jonathan F Bean, Jennifer S Brach, Brian C Clark, David J Clark, Luigi Ferrucci, James Finley and 10 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Experimental gerontology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
21.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.

  1. Pooled it
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  5. Cross-species identification of conserved and divergent locomotor kinematic strategies using AutoGaitA.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  9. The crossroads between osteosarcopenia and intrinsic capacity-a narrative review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 18 institutions in 4 countries.

Katherine A BoyerDepartment of Kinesiology, University of Massachusetts Amherst, MA, USA; Department of Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, USA. Electronic address: kboyer@umass.edu.
Kate L HayesDepartment of Kinesiology, University of Massachusetts Amherst, MA, USA.
Brian R UmbergerSchool of Kinesiology, University of Michigan, USA.
Peter Gabriel AdamczykDepartment of Mechanical Engineering, University of Wisconsin-Madison, USA.
Jonathan F BeanNew England GRECC, VA Boston Healthcare System, Boston, MA, USA; Department of PM&R, Harvard Medical School, Boston, MA, USA; Spaulding Rehabilitation Hospital, Boston, MA, USA.
Jennifer S BrachDepartment of Physical Therapy, University of Pittsburgh, Pittsburgh, PA, USA.
Brian C ClarkOhio Musculoskeletal and Neurological Institute and the Department of Biomedical Sciences, Ohio University, Athens, OH, USA.
David J ClarkBrain Rehabilitation Research Center, Malcom Randall VA Medical Center, Gainesville, FL, USA; Department of Physiology and Aging, University of Florida, Gainesville, FL, USA.
Luigi FerrucciIntramural Research Program of the National Institute on Aging, NIH, Baltimore, MD, USA.
James FinleyDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, USA.
Jason R FranzJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC, USA.
Yvonne M GolightlyCollege of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE, USA; Thurston Arthritis Research Center, Division of Rheumatology, Allergy, and Immunology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Tibor HortobágyiHungarian University of Sports Science, Department of Kinesiology, Budapest, Hungary; Institute of Sport Sciences and Physical Education, University of Pécs, Hungary; Somogy County Kaposi Mór Teaching Hospital, Kaposvár, Hungary; Center for Human Movement Sciences, University of Groningen Medical Center, Groningen, the Netherlands.
Sandra HunterDepartment of Physical Therapy, Marquette University, Milwaukee, WI, USA.
Marco NariciNeuromuscular Physiology Laboratory, Department of Biomedical Sciences, University of Padova, Padova, Italy.
Barbara NicklasSection on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, USA.
Thomas RobertsDepartment of Ecology and Evolutionary Biology, Brown University, USA.
Gregory SawickiGeorge W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, USA.
Eleanor SimonsickIntramural Research Program of the National Institute on Aging, NIH, Baltimore, MD, USA.
Jane A KentDepartment of Kinesiology, University of Massachusetts Amherst, MA, USA.
National Institute on Aging · USUniversity of Massachusetts Amherst · USGeorgia Institute of Technology · USJohn Brown University · USMarquette University · USNorth Carolina State University · USOhio University · USUniversity Medical Center Groningen · NLUniversity of Florida · USUniversity of Massachusetts Chan Medical School · USUniversity of Michigan–Ann Arbor · USUniversity of North Carolina at Chapel Hill · USUniversity of Padua · ITUniversity of Pittsburgh · USUniversity of Southern California · USUniversity of Wisconsin–Madison · USVA Boston Healthcare System · USWake Forest University · US

Funding

Intramural NIH HHS Z99 AG999999
6 · The paper itself

Abstract

Changes in old age that contribute to the complex issue of an increased metabolic cost of walking (mass-specific energy cost per unit distance traveled) in older adults appear to center at least in part on changes in gait biomechanics. However, age-related changes in energy metabolism, neuromuscular function and connective tissue properties also likely contribute to this problem, of which the consequences are poor mobility and increased risk of inactivity-related disease and disability. The U.S. National Institute on Aging convened a workshop in September 2021 with an interdisciplinary group of scientists to address the gaps in research related to the mechanisms and consequences of changes in mobility in old age. The goal of the workshop was to identify promising ways to move the field forward toward improving gait performance, decreasing energy cost, and enhancing mobility for older adults. This report summarizes the workshop and brings multidisciplinary insight into the known and potential causes and consequences of age-related changes in gait biomechanics. We highlight how gait mechanics and energy cost change with aging, the potential neuromuscular mechanisms and role of connective tissue in these changes, and cutting-edge interventions and technologies that may be used to measure and improve gait and mobility in older adults. Key gaps in the literature that warrant targeted research in the future are identified and discussed.

Indexed as

National Institute on Aging (U.S.)WalkingBiomechanical PhenomenaGaitUnited StatesFatigueMobilityMuscle energeticsTendonWearable technology

Identifiers

PMID36693530
PMCPMC10008437
OpenAlexW4318026111

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.