Evidence map›Paper›PMID 36692875›Full record

ArticleAddiction biology2023

Serotonergic and dopaminergic control of impulsivity in gambling disorder.

Valtteri Kaasinen, Emma A Honkanen, Kari Lindholm, Elina Jaakkola, Joonas Majuri, Riitta Parkkola, Tommi Noponen, Tero Vahlberg, Valerie Voon, Luke Clark and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Addiction biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
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  8. Brain-based graph-theoretical predictive modeling to map the trajectory of anhedonia, impulsivity, and hypomania from the human functional connectome.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  9. The Association of Antidepressant Use and Impulse Control Disorder in Parkinson's Disease.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Observational
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 4 countries.

Valtteri KaasinenClinical Neurosciences, Department of Clinical Medicine, Faculty of Medicine, University of Turku, Turku, Finland.ORCID 0000-0002-3446-7093
Emma A HonkanenClinical Neurosciences, Department of Clinical Medicine, Faculty of Medicine, University of Turku, Turku, Finland.
Kari LindholmClinical Neurosciences, Department of Clinical Medicine, Faculty of Medicine, University of Turku, Turku, Finland.
Elina JaakkolaClinical Neurosciences, Department of Clinical Medicine, Faculty of Medicine, University of Turku, Turku, Finland.
Joonas MajuriDepartment of Neurology, North Kymi Hospital, Kouvola, Finland.
Riitta ParkkolaDepartment of Radiology, University of Turku and Turku University Hospital, Turku, Finland.
Tommi NoponenDepartment of Clinical Physiology and Nuclear Medicine, University of Turku and Turku University Hospital, Turku, Finland.
Tero VahlbergBiostatistics, Department of Clinical Medicine, Faculty of Medicine, University of Turku, Turku, Finland.
Valerie VoonDepartment of Psychiatry, University of Cambridge, Cambridge, UK.ORCID 0000-0001-6790-1776
Luke ClarkDepartment of Psychology and Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada.
Juho JoutsaClinical Neurosciences, Department of Clinical Medicine, Faculty of Medicine, University of Turku, Turku, Finland.
Marko SeppänenTurku PET Centre, Turku University Hospital, Turku, Finland.
University of Turku · FINiuvanniemi Hospital · FIUniversity of British Columbia · CAUniversity of Cambridge · GB

Funding

Medical Research Council MR/P008747/1
6 · The paper itself

Abstract

Gambling disorder (GD) is major public health issue. The disorder is often characterized by elevated impulsivity with evidence from analogous substance use disorders underlining prominent roles of brain monoamines in addiction susceptibility and outcome. Critically, GD allows the study of addiction mechanisms without the confounder of the effects of chronic substances. Here, we assessed the roles of striatal dopamine transporter binding and extrastriatal serotonin transporter binding in GD as a function of impulsivity using [

Indexed as

GamblingAgedDopamineDopamine Plasma Membrane Transport ProteinsHumansImpulsive BehaviorMiddle AgedPrefrontal CortexSerotonin Plasma Membrane Transport ProteinsDopamineDopamine Plasma Membrane Transport ProteinsSerotonin Plasma Membrane Transport Proteinsgambling disorderimpulsivitySPECT

Identifiers

PMID36692875
PMCPMC10078603
OpenAlexW4315471004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.