Evidence map›Paper›PMID 36692807›Full record

ReviewCurrent nutrition reports2023

Grape Seed Components as Protectors of Inflammation, DNA Damage, and Cancer.

Melissa Mancini, Maria Eduarda Vieira Cerny, Natali Silva Cardoso, Gesiele Verissimo, Sharbel Weidner Maluf

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current nutrition reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Salubrious effects of proanthocyanidins on behavioral phenotypes and DNA repair deficiency in the BTBR mouse model of autism.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melissa ManciniCytogenetics and Genome Stability Laboratory, University Hospital and Pharmacy Postgraduate Program, Federal University of Santa Catarina, Florianópolis, Brazil.
Maria Eduarda Vieira CernyCytogenetics and Genome Stability Laboratory, University Hospital and Pharmacy Postgraduate Program, Federal University of Santa Catarina, Florianópolis, Brazil.
Natali Silva CardosoCytogenetics and Genome Stability Laboratory, University Hospital and Pharmacy Postgraduate Program, Federal University of Santa Catarina, Florianópolis, Brazil.
Gesiele VerissimoGESIELEVER, Scientific Consultancy, Loosdrecht, The Netherlands.
Sharbel Weidner MalufCytogenetics and Genome Stability Laboratory, University Hospital and Pharmacy Postgraduate Program, Federal University of Santa Catarina, Florianópolis, Brazil. 0808swm@gmail.com.ORCID http://orcid.org/0000-0003-2289-7739

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewOxidative stress is related to the pathogenesis of several chronic diseases, including inflammatory processes. Free radicals excess increase not only oxidative stress but also genomic instability. Polyphenols are non-enzymatic antioxidants that act as a defense barrier against free radicals and non-radical oxidants. The purpose of this article was to review published articles relating dietary polyphenols contained in grape seed proanthocyanidin extracts with its potential for reversing DNA damage. RECENT

findingsProanthocyanidin components exert pleiotropic actions having several biological, biochemical, and significant pharmacological effects and showed the ability to reduce cytotoxicity and genotoxicity. Grape seed proanthocyanidin extracts showed the ability to reduce cytotoxicity and genotoxicity through the comet assay and the micronucleus technique.

Indexed as

Grape Seed ExtractNeoplasmsVitisDNA DamageFree RadicalsHumansInflammationPolyphenolsFree RadicalsGrape Seed ExtractPolyphenolsCancer risk assessmentComet assayCytokinesis-blocked micronucleus (CBMN)Genomic instabilityProanthocyanidins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.