Evidence map›Paper›PMID 36692706›Full record

ArticleNeurology and therapy2023

Proposed Recommendations for the Management of Depression in Adults with Epilepsy: An Expert Consensus.

Vicente Villanueva, Jesús Artal, Clara-Isabel Cabeza-Alvarez, Dulce Campos, Ascensión Castillo, Gerardo Flórez, Manuel Franco-Martin, María Paz García-Portilla, Beatriz G Giráldez, Francisco Gotor and 10 more

Open access · goldAbstract read
In one paragraph

Article in Neurology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 15 institutions in 1 country.

Vicente VillanuevaRefractory Epilepsy Unit, Neurology Service, Hospital Universitario y Politécnico la Fe, Valencia, Spain.ORCID http://orcid.org/0000-0003-2080-8042
Jesús ArtalPsychiatry Department, Hospital Universitario Marqués de Valdecilla, Av. de Valdecilla, 25, 39008, Santander, Spain. jesusartalsimon@gmail.com.ORCID http://orcid.org/0000-0001-5643-3583
Clara-Isabel Cabeza-AlvarezNeurology Department, Hospital Universitario de Toledo, Toledo, Spain.ORCID http://orcid.org/0000-0002-0200-2611
Dulce CamposNeurology Department, University Clinical Hospital of Valladolid, Valladolid, Spain.ORCID http://orcid.org/0000-0003-3582-415X
Ascensión CastilloNeurology Department, Consorcio Hospital General Universitario Valencia, Valencia, Spain.
Gerardo FlórezPsychiatry Department, Addiction Treatment Unit, Orense, Spain.ORCID http://orcid.org/0000-0001-7850-2594
Manuel Franco-MartinPsychiatry Department, Zamora Hospital (Complejo Asistencial de Zamora), Zamora, Spain.ORCID http://orcid.org/0000-0002-3639-2523
María Paz García-PortillaPsychiatry Department, University of Oviedo, ISPA, CIBERSAM, INEUROPA, and Mental Health Services of Principality of Asturias, Oviedo, Spain.ORCID http://orcid.org/0000-0003-3643-1622
Beatriz G GiráldezNeurology Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
Francisco GotorPsychiatry Department, School of Medicine, University Hospital Virgen del Rocio, Seville, Spain.ORCID http://orcid.org/0000-0003-4339-7944
Luis Gutiérrez-RojasPsychiatry Department, Hospital San Cecilio, Granada, Spain.ORCID http://orcid.org/0000-0003-0082-2189
Albert Molins AlbanellNeurology Department, Hospital de Girona-Salt, Salt, Spain.
Gonzalo PaniaguaPsychiatry Department, University of Oviedo, Oviedo, Spain.ORCID http://orcid.org/0000-0003-1415-1291
Luis PintorPsychiatry Department, Hospital Clínico of Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0002-8730-7296
Juan José PozaNeurology Department, Hospital Universitario Donostia, Donostia, Spain.ORCID http://orcid.org/0000-0001-8610-1467
Teresa Rubio-GraneroPsychiatry Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Manuel ToledoEpilepsy Unit, Vall D'Hebron University Hospital, Barcelona, Spain.
Diego Tortosa-ConesaNeurology Department, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain.ORCID http://orcid.org/0000-0002-1857-4382
Juan Rodríguez-UrangaNeurology Department, Centro de Neurología Avanzada (CNA), Seville, Spain.
Julio BobesMedicine-Psychiatry, Universidad de Oviedo, Oviedo, Spain.ORCID http://orcid.org/0000-0003-2187-4033
Universidad de Oviedo · ESHospital Universitari i Politècnic La Fe · ESCentro Nacional de Aceleradores · ESComplejo Hospitalario Universitario de Toledo · ESDonostiako Unibertsitate Ospitalea · ESHospital Clínic de Barcelona · ESHospital General Universitario De Valencia · ESHospital Universitario Fundación Jiménez Díaz · ESHospital Universitario Virgen de la Arrixaca · ESHospital Universitario Virgen del Rocío · ESHospital Virgen de la Concha · ESInstituto de Investigación Biosanitaria de Granada · ESMarqués de Valdecilla University Hospital · ESUniversidad de Valladolid · ESVall d'Hebron Hospital Universitari · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionExperts agree that there is a need for protocols to guide health professionals on how to best manage psychiatric comorbidities in patients with epilepsy (PWE). We aimed to develop practical recommendations for key issues in the management of depression in PWE.

methodsThis was a qualitative study conducted in four steps: (1) development of a questionnaire on the management of depression in PWE to be answered; (2) literature review and, if evidence from guidelines/consensus or systematic reviews was available, drafting initial recommendations; (3) a nominal group methodology for reviewing initial recommendations and formulating new recommendations on those issues without available evidence; and (4) drafting and approving the final recommendations. A scientific committee (one neurologist and one psychiatrist) was responsible for the development of the project and its scientific integrity. The scientific committee selected a panel of experts (nine neurologists and nine psychiatrists with experience in this field) to be involved in the nominal group meetings and to formulate final recommendations.

resultsFifteen recommendations were formulated. Four on the screening and diagnosis: screening and diagnosis of depression, evaluation of the risk of suicide, and diagnosis of depression secondary to epilepsy; nine on the management of depression: referral to a psychiatrist, selection of the antiseizure medication, change of antiseizure medication, antidepressant treatment initiation, selection of antidepressant, use of antidepressants during pregnancy, use of psychotherapy, antidepressant treatment duration, and discontinuation of antidepressant treatment; two on the follow-up: duration of the follow-up under usual conditions, and follow-up of patients at risk of suicide.

conclusionWe provide recommendations based on expert opinion consensus to help healthcare professionals assess depression in PWE. The detection and treatment of major depressive disorders are key factors in improving epilepsy outcomes and avoiding suicide risk.

Indexed as

DepressionDiagnosisEpilepsyExpert consensusSuicide riskTreatment

Identifiers

PMID36692706
PMCPMC10043101
OpenAlexW4317838311

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.