Evidence map›Paper›PMID 36692700›Full record

ArticleInternational ophthalmology2023

Meibomian gland secretion quality association with ocular parameters in university students during COVID- 19 restrictions.

Jacobo Garcia-Queiruga, Hugo Pena-Verdeal, Belén Sabucedo-Villamarin, Maria J Giraldez, Carlos Garcia-Resua, Eva Yebra-Pimentel

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Meibum Lipidomic Analysis in Evaporative Dry Eye Subjects.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jacobo Garcia-QueirugaGI-2092 - Optometry, Department of Applied Physics (Optometry Area), Universidade de Santiago de Compostela, Campus Vida s/n, Santiago de Compostela, Spain. jacobogarcia.queiruga@usc.es.
Hugo Pena-VerdealGI-2092 - Optometry, Department of Applied Physics (Optometry Area), Universidade de Santiago de Compostela, Campus Vida s/n, Santiago de Compostela, Spain.
Belén Sabucedo-VillamarinGI-2092 - Optometry, Department of Applied Physics (Optometry Area), Universidade de Santiago de Compostela, Campus Vida s/n, Santiago de Compostela, Spain.
Maria J GiraldezGI-2092 - Optometry, Department of Applied Physics (Optometry Area), Universidade de Santiago de Compostela, Campus Vida s/n, Santiago de Compostela, Spain.
Carlos Garcia-ResuaGI-2092 - Optometry, Department of Applied Physics (Optometry Area), Universidade de Santiago de Compostela, Campus Vida s/n, Santiago de Compostela, Spain.
Eva Yebra-PimentelGI-2092 - Optometry, Department of Applied Physics (Optometry Area), Universidade de Santiago de Compostela, Campus Vida s/n, Santiago de Compostela, Spain.
Universidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine if the Meibomian Gland (MG) secretion quality is associated with symptoms of ocular discomfort, hours of Video Display Terminals (VDT) use, eyelid margin abnormalities, conjunctival hyperemia, and Meibomian Gland Loss Area (MGLA) in a sample of university students.

methodsAn online survey that included an Ocular Surface Disease Index (OSDI) questionnaire and an extra question about hours of VDT use recruited an initial sample of 183 participants. Only 120 participants that fulfilled the inclusion criteria were scheduled for a battery of ocular surface and MG specific exam. The tests include: 1) meibometry, 2) slit lamp exploration of eyelid margin abnormalities (irregularity, hyperemia and MG orifices plugging), MG secretion quality and conjunctival hyperemia, and 3) Meibography.

resultsSignificant positive correlations between the MG secretion quality and eyelid margin hyperemia, MG orifices plugging, MGLA, nasal conjunctival hyperemia, and temporal conjunctival hyperemia (Spearman Rho; all r>0.186, p<0.042) were found. Multivariate regression found association between OSDI with hours of VDT use (B=0.316, p=0.007), and eyelid hyperemia (B=0.434, p≤ 0.001). A statistical association between MG secretion quality and eyelid margin hyperemia, MG orifices plugging, MGLA and conjunctival hyperemia (Fisher's exact; all p<0.039) were found. Multivariate regression found association between MG secretion quality with MG orifices plugging (B=0.295, p=0.004) and meibometry (B=-0.001, p=0.029).

conclusionParticipants with higher values in MG secretion quality have higher values in eyelid margin hyperemia, MG plugging, MGLA, and conjunctival hyperemia. No direct relationship between MG secretion quality and hours of VDT use or OSDI were found.

Indexed as

COVID-19Dry Eye SyndromesEyelid DiseasesHyperemiaHumansMeibomian GlandsStudentsTearsUniversitiesEyelid abnormalitiesMeibomian gland loss areaMeibomian gland orifice pluggingMeibomian gland secretion qualityVideo display terminals

Identifiers

PMID36692700
PMCPMC9873396
OpenAlexW4317871438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.