Evidence map›Paper›PMID 36692684›Full record

ArticleNeurotoxicity research2023

Modulatory Role of Curcumin on Cobalt-Induced Memory Deficit, Hippocampal Oxidative Damage, Astrocytosis, and Nrf2 Expression.

Rademene S Oria, Godson E Anyanwu, Emmanuel A Esom, Johnson N Nto, Amechi U Katchy, Augustine U Agu, Omamuyovwi M Ijomone

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Neurotoxicity research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Exploring the interactions between curcumin and cobalt: implications for health and toxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Fisetin attenuates AlClToxicology reports · 2024
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rademene S OriaDepartment of Anatomy, College of Medicine, Faculty of Basic Medical Sciences, University of Nigeria, Nsukka, Enugu Campus, Nsukka, Nigeria.ORCID http://orcid.org/0000-0002-7233-7361
Godson E AnyanwuDepartment of Anatomy, College of Medicine, Faculty of Basic Medical Sciences, University of Nigeria, Nsukka, Enugu Campus, Nsukka, Nigeria. anyanwugemeks@yahoo.com.ORCID http://orcid.org/0000-0002-7367-807X
Emmanuel A EsomDepartment of Anatomy, College of Medicine, Faculty of Basic Medical Sciences, University of Nigeria, Nsukka, Enugu Campus, Nsukka, Nigeria.ORCID http://orcid.org/0000-0003-2355-2775
Johnson N NtoDepartment of Anatomy, College of Medicine, Faculty of Basic Medical Sciences, University of Nigeria, Nsukka, Enugu Campus, Nsukka, Nigeria.ORCID http://orcid.org/0000-0001-9601-9870
Amechi U KatchyDepartment of Anatomy, College of Medicine, Faculty of Basic Medical Sciences, University of Nigeria, Nsukka, Enugu Campus, Nsukka, Nigeria.ORCID http://orcid.org/0000-0002-3681-3404
Augustine U AguDepartment of Anatomy, College of Medicine, Faculty of Basic Medical Sciences, University of Nigeria, Nsukka, Enugu Campus, Nsukka, Nigeria.ORCID http://orcid.org/0000-0002-8615-1947
Omamuyovwi M IjomoneThe Neuro-Lab, School of Basic Medical Sciences, Federal University of Technology, Akure, Nigeria.ORCID http://orcid.org/0000-0002-0933-8409
University of Nigeria · NGFederal University of Technology · NG

Funding

Tertiary Education Trust Fund TETF/DR&D/CE/UNI/CALABAR/IBR/2019/VOL.1
6 · The paper itself

Abstract

Chemical overexposure is a growing environmental risk factor for many medical issues. Cobalt toxicity from environmental, industrial, and medical exposure has previously been linked to neurological impairment. Hence, the current study looked into the neuroprotective potential of curcumin, a natural polyphenol contained in the spice turmeric, against cobalt-induced neurotoxicity. Adult rats were randomly divided into six groups as follows: control, 40 mg/kg cobalt chloride (CoCl

Indexed as

CurcuminNF-E2-Related Factor 2AnimalsAscorbic AcidCobaltGliosisHippocampusMemory DisordersOxidative StressRatsAscorbic AcidCobaltcobaltous chlorideCurcuminNF-E2-Related Factor 2CobaltCurcuminDentate gyrusHippocampusNeurodegenerationOxidative stress

Identifiers

PMID36692684
OpenAlexW4317829667

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.