ArticleEuropean journal of nutrition2023
Serum 25-hydroxyvitamin D status of a large Chinese population from 30 provinces by LC-MS/MS measurement for consecutive 3 years: differences by age, sex, season and province.
Article in European journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Maternal hypertensive disorders during pregnancy and their link to childhood asthma: a systematic review and meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Th2 and Th17/Th1 Inflammatory Profiles in Chronic Rhinosinusitis: Associations with Vitamin D Status and Disease Severity.International journal of molecular sciences · 2026Article
- Vitamin D status and site-specific fracture pattern associations in older adults with fragility fractures: a cross-sectional analysis of 2543 patients.Frontiers in nutrition · 2026Article
- A decade-long assessment reveals persistent vitamin D deficiency and its associated factors in early-pregnant women from northern China (2016-2025).Frontiers in nutrition · 2026Article
- Association Between Serum Vitamin D Levels and Metformin Efficacy in Obese Type 2 Diabetes Patients: A Retrospective Cohort Study Based on HbA1c Reduction.Therapeutics and clinical risk management · 2026Article
- Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong.European journal of nutrition · 2025Article
- Association between serum vitamin D level and cardiovascular disease in Chinese patients with type 2 diabetes mellitus: a cross-sectional study.Scientific reports · 2025Article
- Assessment of vitamin D nutritional status among adults in Lu'an, China, based on serum 25-hydroxyvitamin D measured by LC-MS/MS.Frontiers in nutrition · 2025Article
- High prevalence and seasonal patterns of vitamin D deficiency in children and adolescents in Central China: a three-year single-center study.Preventive medicine reports · 2024Article
- Assessment of serum vitamin D levels in children aged 0-17 years old in a Chinese population: a comprehensive study.Scientific reports · 2024Article
- Discordant Health Implications and Molecular Mechanisms of Vitamin D in Clinical and Preclinical Studies of Prostate Cancer: A Critical Appraisal of the Literature Data.International journal of molecular sciences · 2024Review
- Vitamin D Deficiency and Associated Factors in Children: A Multicenter Study of 21,811 Samples in Southern China.International journal of public health · 2024Article
- Serum 25-hydroxyvitamin D level is associated with short-term glycemic variability metrics derived from continuous glucose monitoring in T2DM.Scientific reports · 2023Article
- Serum 25-Hydroxy Vitamin D Levels in Children with Acute Respiratory Infections Caused by Respiratory Virus or Atypical Pathogen Infection.Nutrients · 2023Article
- Association Between Sensitivity to Thyroid Hormones and Metabolic Dysfunction-Associated Fatty Liver Disease in Euthyroid Subjects: A Cross-Sectional Study [Letter].Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Association Between Trichoscopic Features and Serum Hormone Levels and Vitamin D Concentration in Patients with Androgenetic Alopecia in Eastern China: A Cross-Sectional Study.Clinical, cosmetic and investigational dermatology · 2023Article
- Vitamin D status in children.Jornal de pediatriaArticle
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
Abstract
purposeWe aimed to describe the vitamin D status and its distribution in different age groups, sexes, seasons, and provinces of a large Chinese population.
methodsThis study retrospectively analyzed 1,528,685 results of serum 25-hydroxyvitamin D (25(OH)D) in the central laboratory of KingMed Diagnostics. The samples were from the individuals aged 0-119 years old in 30 provinces of China. Serum 25(OH)D was measured by an accurate commercial liquid chromatography-tandem mass spectrometry (LC-MS/MS) method from January 2017 to December 2019. The subjects were stratified by age, sex, the season of blood collection, and the province of residence.
resultsThe median 25(OH)D concentration was 25.5 ng/mL (interquartile range (IQR) 18.7-32.7 ng/mL) in males and 20.8 ng/mL (IQR 14.4-28.2 ng/mL) in females. Overall, the median 25(OH)D concentration decreased with age in both males and females. Males had a 0.2-2.4 ng/mL higher median 25(OH)D concentration than females in different age groups. Vitamin D deficiency (25(OH)D < 15 ng/mL for the individuals under 14 years old; < 20 ng/mL for the individuals over 14 years old) was found in 21.3% of males and 43.6% of females. Significant seasonal variation of serum 25(OH)D concentrations was repeatedly observed in 3 years, with median concentration higher in summer (25.3 ng/mL (IQR 19.3-31.9 ng/mL)) and lower in winter (18.5 ng/mL (IQR 12.3-26.6 ng/mL)). Vitamin D status varied by province. The median 25(OH)D concentration was the highest in Hainan (31.0 ng/mL (IQR 24.9-39.2 ng/mL)) and the lowest in Qinghai (14.4 ng/mL (IQR 9.6-20.0 ng/mL)). 25(OH)D
conclusionIn China, vitamin D deficiency is prevalent in the population participating in clinical vitamin D measurement. Age and sex differences in vitamin D levels were observed in our study. Seasonal variation and provincial differences are important aspects of serum vitamin D status. 25(OH)D
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