Evidence map›Paper›PMID 36692486›Full record

ArticleGlobal health action2023

Identifying the necessary capacities for the adaptation of a diabetes phenotyping algorithm in countries of differing economic development status.

Angela Jackson-Morris, Rita Sembajwe, Feisul Idzwan Mustapha, Arunah Chandran, Simon Pierre Niyonsenga, Crispin Gishoma, Elizabeth Onyango, Zachariah Muriuki, Kavita Dharamraj, Nathan Ellermeier and 2 more

Open access · goldAbstract read
In one paragraph

Article in Global health action, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Angela Jackson-MorrisCenter for Global Noncommunicable Diseases (AJM, RN, NE), RS Social, Statistical, and Environmental Sciences, RTI International, Seattle, WA, USA.ORCID 0000-0001-8348-7077
Rita SembajweCenter for Global Noncommunicable Diseases (AJM, RN, NE), RS Social, Statistical, and Environmental Sciences, RTI International, Seattle, WA, USA.
Feisul Idzwan MustaphaNCD section, Disease Control Division, Malaysia Ministry of Health, Kuala Lumpur, Malaysia.
Arunah ChandranNCD section, Disease Control Division, Malaysia Ministry of Health, Kuala Lumpur, Malaysia.
Simon Pierre NiyonsengaDepartment of Biotechnology, Rwanda Biomedical Centre, Kigali, Rwanda.
Crispin GishomaRwanda Diabetes Association, Kigali, Rwanda.
Elizabeth OnyangoDivision of Non-Communicable Disease Prevention and Control, Kenya Ministry of Health, Nairobi, Kenya.
Zachariah MuriukiDivision of Non-Communicable Disease Prevention and Control, Kenya Ministry of Health, Nairobi, Kenya.
Kavita DharamrajSouth Western Regional Health Authority, Princes Town, Trinidad and Tobago.
Nathan EllermeierCenter for Global Noncommunicable Diseases, Consultant, Durham, NC, USA.
Rachel NugentCenter for Global Noncommunicable Diseases (AJM, RN, NE), RS Social, Statistical, and Environmental Sciences, RTI International, Seattle, WA, USA.ORCID 0000-0001-6421-9077
Rasa KazlauskaiteDepartment of Internal Medicine, RUSH University Medical Center, Chicago, IL, USA.
RTI International · USMinistry of Health · KEMinistry of Health · MYRush University Medical Center · USRwanda Biomedical Center · RWRwanda Diabetes Association · RW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2019, the World Health Organization recognised diabetes as a clinically and pathophysiologically heterogeneous set of related diseases. Little is currently known about the diabetes phenotypes in the population of low- and middle-income countries (LMICs), yet identifying their different risks and aetiology has great potential to guide the development of more effective, tailored prevention and treatment.

objectivesThis study reviewed the scope of diabetes datasets, health information ecosystems, and human resource capacity in four countries to assess whether a diabetes phenotyping algorithm (developed under a companion study) could be successfully applied.

methodsThe capacity assessment was undertaken with four countries: Trinidad, Malaysia, Kenya, and Rwanda. Diabetes programme staff completed a checklist of available diabetes data variables and then participated in semi-structured interviews about Health Information System (HIS) ecosystem conditions, diabetes programme context, and human resource needs. Descriptive analysis was undertaken.

resultsOnly Malaysia collected the full set of the required diabetes data for the diabetes algorithm, although all countries did collect the required diabetes complication data. An HIS ecosystem existed in all settings, with variations in data hosting and sharing. All countries had access to HIS or ICT support, and epidemiologists or biostatisticians to support dataset preparation and algorithm application.

conclusionsMalaysia was found to be most ready to apply the phenotyping algorithm. A fundamental impediment in the other settings was the absence of several core diabetes data variables. Additionally, if countries digitise diabetes data collection and centralise diabetes data hosting, this will simplify dataset preparation for algorithm application. These issues reflect common LMIC health systems' weaknesses in relation to diabetes care, and specifically highlight the importance of investment in improving diabetes data, which can guide population-tailored prevention and management approaches.

Indexed as

Diabetes MellitusEcosystemAlgorithmsDeveloping CountriesEconomic DevelopmentHumansSocioeconomic FactorsDiabeteshealth information systemLMICsnon-communicable diseasesphenotype

Identifiers

PMID36692486
PMCPMC9879185
OpenAlexW4317870176

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.