Evidence map›Paper›PMID 36692337›Full record

ArticleEmerging infectious diseases2023

Incidence and Transmission Dynamics of Bordetella pertussis Infection in Rural and Urban Communities, South Africa, 2016‒2018.

Fahima Moosa, Stefano Tempia, Jackie Kleynhans, Meredith McMorrow, Jocelyn Moyes, Mignon du Plessis, Maimuna Carrim, Florette K Treurnicht, Orienka Helferscee, Thulisa Mkhencele and 9 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. [Pertussis worldwide. Vaccinating children and adults].Medecine tropicale et sante internationale · 2023
    Article
  6. Article
  7. Genomic characterization ofMicrobial genomics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Fahima Moosa
Stefano Tempia
Jackie Kleynhans
Meredith McMorrow
Jocelyn Moyes
Mignon du Plessis
Maimuna Carrim
Florette K Treurnicht
Orienka Helferscee
Thulisa Mkhencele
Azwifarwi Mathunjwa
Neil A Martinson
Kathleen Kahn
Limakatso Lebina
Floidy Wafawanaka
Cheryl Cohen
Anne von Gottberg
Nicole Wolter
PHIRST Group

Funding

South African Preparedness for Rapid Detection of Highly Pathogenic Avian InfluenU51IP000155 · IP · NATIONAL INST FOR COMMUNICABLE DISEASES · PI VENTER, MARIETJIE · 2007 to 2010
$6.7M
Southern African-Pittsburgh Public Health Genomic Epidemiology Training Program (SAPPHGenE)D43TW011255 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Lee H Harrison, Anne von Gottberg · 2019 to 2026
$1.7M
FIC NIH HHS D43 TW011255NCIRD CDC HHS U51 IP000155Wellcome TrustWellcome Trust 058893/Z/99/AWellcome Trust 069683/Z/02/ZWellcome Trust 085477/B/08/ZWellcome Trust 085477/Z/08/Z
6 · The paper itself

Abstract

We conducted 3 prospective cohort studies (2016-2018), enrolling persons from 2 communities in South Africa. Nasopharyngeal swab specimens were collected twice a week from participants. Factors associated with Bordetella pertussis incidence, episode duration, and household transmission were determined by using Poisson regression, Weibull accelerated time-failure, and logistic regression hierarchical models, respectively. Among 1,684 participants, 118 episodes of infection were detected in 107 participants (incidence 0.21, 95% CI 0.17-0.25 infections/100 person-weeks). Children <5 years of age who had incomplete vaccination were more likely to have pertussis infection. Episode duration was longer for participants who had higher bacterial loads. Transmission was more likely to occur from male index case-patients and persons who had >7 days infection duration. In both communities, there was high incidence of B. pertussis infection and most cases were colonized.

Indexed as

Whooping CoughBordetella pertussisChildHumansIncidenceMaleProspective StudiesSouth AfricabacteriaBordetella pertussiscohort studycolonizationhousehold transmissionincidenceincidence and transmission dynamicsinfectionpertussisrespiratory infectionsrural and urban communitiesSouth Africawhooping cough

Identifiers

PMID36692337
PMCPMC9881781

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.