Evidence map›Paper›PMID 36692297›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2023

Methyl-Based Methanogenesis: an Ecological and Genomic Review.

Clifton P Bueno de Mesquita, Dongying Wu, Susannah G Tringe

Abstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Trial
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  8. An integrated culturomic and genomic database and analysis platform for methanogenic archaea.Database : the journal of biological databases and curation · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
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  15. Microbial oxidation significantly reduces methane export from global groundwaters.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Clifton P Bueno de MesquitaDepartment of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.ORCID 0000-0002-2565-7100
Dongying WuDepartment of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.ORCID 0000-0002-4167-2212
Susannah G TringeDepartment of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.ORCID 0000-0001-6479-8427

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methyl-based methanogenesis is one of three broad categories of archaeal anaerobic methanogenesis, including both the methyl dismutation (methylotrophic) pathway and the methyl-reducing (also known as hydrogen-dependent methylotrophic) pathway. Methyl-based methanogenesis is increasingly recognized as an important source of methane in a variety of environments. Here, we provide an overview of methyl-based methanogenesis research, including the conditions under which methyl-based methanogenesis can be a dominant source of methane emissions, experimental methods for distinguishing different pathways of methane production, molecular details of the biochemical pathways involved, and the genes and organisms involved in these processes. We also identify the current gaps in knowledge and present a genomic and metagenomic survey of methyl-based methanogenesis genes, highlighting the diversity of methyl-based methanogens at multiple taxonomic levels and the widespread distribution of known methyl-based methanogenesis genes and families across different environments.

Indexed as

ArchaeaEuryarchaeotaHumansMetagenomicsMethaneMethaneanaerobic catabolic pathwaysArchaeamethanemethanogenesismethanogensmethylated compoundsmethylotrophs

Identifiers

PMID36692297
PMCPMC10029344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.