Evidence map›Paper›PMID 36692269›Full record

ArticleeLife2023

A hardware system for real-time decoding of in vivo calcium imaging data.

Zhe Chen, Garrett J Blair, Changliang Guo, Jim Zhou, Juan-Luis Romero-Sosa, Alicia Izquierdo, Peyman Golshani, Jason Cong, Daniel Aharoni, Hugh T Blair

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. FPGA-Based In-Vivo Calcium Image Decoding for Closed-Loop Feedback Applications.IEEE transactions on biomedical circuits and systems · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zhe ChenDepartment of Electrical and Computer Engineering, University of California, Los Angeles, Los Angeles, United States.
Garrett J BlairDepartment of Psychology, University of California, Los Angeles, Los Angeles, United States.ORCID 0000-0003-2724-8914
Changliang GuoDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.
Jim ZhouDepartment of Electrical and Computer Engineering, University of California, Los Angeles, Los Angeles, United States.
Juan-Luis Romero-SosaDepartment of Psychology, University of California, Los Angeles, Los Angeles, United States.
Alicia IzquierdoDepartment of Psychology, University of California, Los Angeles, Los Angeles, United States.ORCID 0000-0001-9897-2091
Peyman GolshaniDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.
Jason CongDepartment of Electrical and Computer Engineering, University of California, Los Angeles, Los Angeles, United States.
Daniel AharoniDavid Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.ORCID 0000-0003-4931-8514
Hugh T BlairDepartment of Psychology, University of California, Los Angeles, Los Angeles, United States.ORCID 0000-0001-8256-5109
University of California, Los Angeles · US

Funding

An Open Source, Wireless, Miniature Microscope for Monitoring Neuronal ActivityUF1NS107668 · NINDS · UNIVERSITY OF WASHINGTON · PI BASSO, MICHELE A, GOLSHANI, PEYMAN · 2018 to 2018
$3.7M
Frontocortical Signaling Signatures in Flexible Reinforcement LearningR21MH122800 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BLAIR, HUGH T, IZQUIERDO, ALICIA · 2021 to 2022
$429k
NIMH NIH HHS R21 MH122800NINDS NIH HHS UF1 NS107668
6 · The paper itself

Abstract

Epifluorescence miniature microscopes ('miniscopes') are widely used for in vivo calcium imaging of neural population activity. Imaging data are typically collected during a behavioral task and stored for later offline analysis, but emerging techniques for online imaging can support novel closed-loop experiments in which neural population activity is decoded in real time to trigger neurostimulation or sensory feedback. To achieve short feedback latencies, online imaging systems must be optimally designed to maximize computational speed and efficiency while minimizing errors in population decoding. Here we introduce

Indexed as

CalciumComputersAnimalsMicroscopyRatsCalciumcalcium imagingclosed-loopcomputational biologyneural decodingneuroscienceratsystems biology

Identifiers

PMID36692269
PMCPMC9908073
OpenAlexW4317871205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.