Evidence map›Paper›PMID 36691744›Full record

ArticleProtein science : a publication of the Protein Society2023

Structural investigation of CDCA3-Cdh1 protein-protein interactions using in vitro studies and molecular dynamics simulation.

Tabassum Khair Barbhuiya, Mark Fisher, Eric D Boittier, Emma Bolderson, Kenneth J O'Byrne, Derek J Richard, Mark Nathaniel Adams, Neha S Gandhi

Open access · hybridAbstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Tabassum Khair BarbhuiyaCentre for Genomics and Personalised Health, and School of Chemistry and Physics, Faculty of Science, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID 0000-0001-8975-4877
Mark FisherCancer and Ageing Research Program, Woolloongabba, Queensland, Australia.ORCID 0000-0003-3422-454X
Eric D BoittierDepartment of Chemistry, University of Basel, Basel, Switzerland.ORCID 0000-0002-9611-1017
Emma BoldersonCancer and Ageing Research Program, Woolloongabba, Queensland, Australia.ORCID 0000-0002-2849-1177
Kenneth J O'ByrneCancer and Ageing Research Program, Woolloongabba, Queensland, Australia.ORCID 0000-0002-6754-5633
Derek J RichardCancer and Ageing Research Program, Woolloongabba, Queensland, Australia.ORCID 0000-0002-4839-8471
Mark Nathaniel AdamsCancer and Ageing Research Program, Woolloongabba, Queensland, Australia.ORCID 0000-0003-1906-5018
Neha S GandhiCentre for Genomics and Personalised Health, and School of Chemistry and Physics, Faculty of Science, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID 0000-0003-3119-6731
Translational Research Institute · AUUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase and its cofactor, Cdh1, regulate the expression of several cell-cycle proteins and their functions during mitosis. Levels of the protein cell division cycle-associated protein 3 (CDCA3), which is functionally required for mitotic entry, are regulated by APC/C

Indexed as

Cell Cycle ProteinsMolecular Dynamics SimulationAnaphase-Promoting Complex-CyclosomeCdh1 ProteinsCell CycleAnaphase-Promoting Complex-CyclosomeCdh1 ProteinsCell Cycle Proteinsanaphase-promoting complex/cyclosomeCDCA3Cdh1co-immunoprecipitationmolecular dynamics simulationpairwise energy decomposition

Identifiers

PMID36691744
PMCPMC9926468
OpenAlexW4317866918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.