Evidence map›Paper›PMID 36691646›Full record

ReviewNeurobiology of stress2023

Effects of neuromodulation on cognitive and emotional responses to psychosocial stressors in healthy humans.

Tabitha E H Moses, Elizabeth Gray, Nicholas Mischel, Mark K Greenwald

Open access · goldAbstract readReview
In one paragraph

Review in Neurobiology of stress, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tabitha E H MosesDept. of Psychiatry and Behavioral Neurosciences, Wayne State University, School of Medicine, Detroit, MI, USA.
Elizabeth GrayDept. of Psychiatry and Behavioral Neurosciences, Wayne State University, School of Medicine, Detroit, MI, USA.
Nicholas MischelDept. of Psychiatry and Behavioral Neurosciences, Wayne State University, School of Medicine, Detroit, MI, USA.
Mark K GreenwaldDept. of Psychiatry and Behavioral Neurosciences, Wayne State University, School of Medicine, Detroit, MI, USA.
Wayne State University · US

Funding

Neuromodulation of stress-induced dysfunction and drug-seeking in opioid use disorder: comparison of fronto-cortical targetsF30DA052118 · NIDA · WAYNE STATE UNIVERSITY · PI MOSES, TABITHA EMILY HOWARD · 2021 to 2024
$196k
NIDA NIH HHS F30 DA052118
6 · The paper itself

Abstract

Physiological and psychological stressors can exert wide-ranging effects on the human brain and behavior. Research has improved understanding of how the sympatho-adreno-medullary (SAM) and hypothalamic-pituitary-adrenocortical (HPA) axes respond to stressors and the differential responses that occur depending on stressor type. Although the physiological function of SAM and HPA responses is to promote survival and safety, exaggerated psychobiological reactivity can occur in psychiatric disorders. Exaggerated reactivity may occur more for certain types of stressors, specifically, psychosocial stressors. Understanding stressor effects and how the body regulates these responses can provide insight into ways that psychobiological reactivity can be modulated. Non-invasive neuromodulation is one way that responding to stressors may be altered; research into these interventions may provide further insights into the brain circuits that modulate stress reactivity. This review focuses on the effects of acute psychosocial stressors and how neuromodulation might be effective in altering stress reactivity. Although considerable research into stress interventions focuses on treating pathology, it is imperative to first understand these mechanisms in non-clinical populations; therefore, this review will emphasize populations with no known pathology and consider how these results may translate to those with psychiatric pathologies.

Indexed as

InterventionNeuromodulationrTMSStresstDCS

Identifiers

PMID36691646
PMCPMC9860364
OpenAlexW4315498871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.