Evidence map›Paper›PMID 36691218›Full record

ArticleBMJ open2022

Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study.

Bridie Angela Evans, Ashley Akbari, Rowena Bailey, Lesley Bethell, Samantha Bufton, Andrew Carson-Stevens, Lucy Dixon, Adrian Edwards, Ann John, Stephen Jolles and 9 more

Abstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Bridie Angela EvansSwansea University Medical School, Swansea, UK b.a.evans@swansea.ac.uk.ORCID 0000-0003-0293-0888
Ashley AkbariSwansea University Medical School, Swansea, UK.ORCID 0000-0003-0814-0801
Rowena BaileySwansea University Medical School, Swansea, UK.
Lesley BethellSwansea University Medical School, Swansea, UK.
Samantha BuftonKnowledge and Analytical Services, Welsh Government, Cardiff, UK.
Andrew Carson-StevensDivision of Population Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0002-7580-7699
Lucy DixonSwansea University Medical School, Swansea, UK.
Adrian EdwardsDivision of Population Medicine, Cardiff University, Cardiff, UK.ORCID 0000-0002-6228-4446
Ann JohnSwansea University Medical School, Swansea, UK.ORCID 0000-0002-5657-6995
Stephen JollesUniversity Hospital of Wales, Cardiff, UK.
Mark Rhys KingstonSwansea University Medical School, Swansea, UK.
Jane LyonsSwansea University Medical School, Swansea, UK.ORCID 0000-0002-4407-770X
Ronan LyonsSwansea University Medical School, Swansea, UK.ORCID 0000-0001-5225-000X
Alison PorterSwansea University Medical School, Swansea, UK.ORCID 0000-0002-3408-7007
Bernadette SewellSwansea Centre for Health Economics, Swansea University, Swansea, West Glamorgan, UK.
Catherine A ThorntonSwansea University Medical School, Swansea, UK.
Alan WatkinsSwansea University Medical School, Swansea, UK.ORCID 0000-0003-3804-1943
Tony WhiffenKnowledge and Analytical Services, Welsh Government, Cardiff, UK.ORCID 0000-0002-9329-6685
Helen SnooksSwansea University Medical School, Swansea, UK.

Funding

British Heart FoundationChief Scientist OfficeDepartment of HealthMedical Research Council MC_PC_20060Medical Research Council MR/V028367/1Wellcome Trust
6 · The paper itself

Abstract

introductionShielding aimed to protect those predicted to be at highest risk from COVID-19 and was uniquely implemented in the UK during the COVID-19 pandemic. Clinically extremely vulnerable people identified through algorithms and screening of routine National Health Service (NHS) data were individually and strongly advised to stay at home and strictly self-isolate even from others in their household. This study will generate a logic model of the intervention and evaluate the effects and costs of shielding to inform policy development and delivery during future pandemics. METHODS AND ANALYSIS: This is a quasiexperimental study undertaken in Wales where records for people who were identified for shielding were already anonymously linked into integrated data systems for public health decision-making. We will: interview policy-makers to understand rationale for shielding advice to inform analysis and interpretation of results; use anonymised individual-level data to select people identified for shielding advice in March 2020 and a matched cohort, from routine electronic health data sources, to compare outcomes; survey a stratified random sample of each group about activities and quality of life at 12 months; use routine and newly collected blood data to assess immunity; interview people who were identified for shielding and their carers and NHS staff who delivered healthcare during shielding, to explore compliance and experiences; collect healthcare resource use data to calculate implementation costs and cost-consequences. Our team includes people who were shielding, who used their experience to help design and deliver this study. ETHICS AND DISSEMINATION: The study has received approval from the Newcastle North Tyneside 2 Research Ethics Committee (IRAS 295050). We will disseminate results directly to UK government policy-makers, publish in peer-reviewed journals, present at scientific and policy conferences and share accessible summaries of results online and through public and patient networks.

Indexed as

COVID-19State MedicineHumansPandemicsPatient ComplianceQuality of LifeWalesCOVID-19health policyimmunologypublic health

Identifiers

PMID36691218
PMCPMC9461087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.