Evidence map›Paper›PMID 36691159›Full record

ArticleBMJ open2022

Antimicrobial prescribing for children in China: data from point prevalence surveys in 18 tertiary centres in China in 2016-2017.

Jiaosheng Zhang, Wenshuang Zhang, Xiang Ma, Lanfang Tang, Daiyin Tian, Keye Wu, Yuejie Zheng, Kunling Shen, Jikui Deng, Yonghong Yang

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Jiaosheng Zhang *Department of Infectious Diseases, Shenzhen Children's Hospital, Shenzhen, China.ORCID 0000-0003-2044-5608
Wenshuang Zhang *Department of Respiratory, Tianjin Children's Hospital, Tianjin, China.
Xiang MaDepartment of Respiratory, Children's Hospital Affiliated to Shandong University & Jinan Children's Hospital, Ji'nan, China.
Lanfang TangDepartment of Respiratory, Children's Hospital Zhejiang University School of Medicine, Hangzhou, China.
Daiyin TianDepartment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing, Chongqing, China.
Keye WuDepartment of Cardiothoracic Surgery, Shenzhen Children's Hospital, Shenzhen, China.
Yuejie ZhengDepartment of Respiratory, Shenzhen Children's Hospital, Shenzhen, China.
Kunling ShenDepartment of Respiration, Beijing Children's Hospital Affiliated to Capital Medical University, Beijing, China.
Jikui DengDepartment of Infectious Diseases, Shenzhen Children's Hospital, Shenzhen, China.
Yonghong YangDepartment of Infectious Diseases, Shenzhen Children's Hospital, Shenzhen, China yyh628628@sina.com.
Shenzhen Children's Hospital · CNCapital Medical University · CNChildren's Hospital of Chongqing Medical University · CNChildren's Hospital of Zhejiang University · CNShandong University · CNTianjin Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe reports on evaluating the classification of antibiotic agents prescribed for Chinese children by combining WHO's and China's administrative categories were rare. This study aimed to investigate the pattern of antimicrobial agents prescribing for Chinese children in 2016. SETTINGS: 18 tertiary centres from nine provinces located in northern, southern, eastern and western China.

participantsThe antimicrobial prescribing data from the children admitted in medical wards, surgical wards and intensive care units were collected and analysed. A total of 3680 antibiotic prescriptions for Chinese children were included in the analysis. PRIMARY AND SECONDARY OUTCOME MEASURES: One-day point-prevalence surveys (PPSs) on antimicrobial prescribing were conducted among hospitalised children in China between 1 February 2016 and 28 February 2017. Five hospitals participated in the first PPS, 13 hospitals in the second PPS, 17 hospitals in the third PPS and 18 hospitals in the fourth PPS. Patterns of antibiotic use with a drug utilisation of 90%, Anatomical Therapeutical Chemical Classification, WHO Access, Watch and Reserve (AWaRe) (version 2019) and antibiotic classification in China were described retrospectively.

resultsA total of 4442 children and 3680 antibiotic prescriptions for Chinese children were included in the analysis. 2900 (65.3%) children received at least one ongoing antibiotic during the survey days. On the basis of WHO AWaRe classification, the proportion of antibiotics in the Watch group was 76.5% (2814/3680). According to the Management of Antibiotic Classification in China, 56.8% (2089/3680) and 16.1% (594/3680) of antibiotic prescriptions in the Restricted group and the Special group, respectively, were included into broad-spectrum antibiotics. The most common indication for antibiotics was bacterial lower respiratory tract infection (2044/3680, 55.5%).

conclusionsThe use of broad-spectrum antibiotics was frequent and excessive in hospitalised children in China in 2016.

Indexed as

Anti-Infective AgentsBacterial InfectionsAnti-Bacterial AgentsChildChinaDrug PrescriptionsHealth Care SurveysHumansPrevalenceRetrospective StudiesAnti-Bacterial AgentsAnti-Infective AgentsCLINICAL PHARMACOLOGYEPIDEMIOLOGYPAEDIATRICSPUBLIC HEALTH

Identifiers

PMID36691159
PMCPMC9442487
OpenAlexW4294267010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.