Evidence map›Paper›PMID 36690870›Full record

ArticleInsights into imaging2023

Generalizable transfer learning of automated tumor segmentation from cervical cancers toward a universal model for uterine malignancies in diffusion-weighted MRI.

Yu-Chun Lin, Yenpo Lin, Yen-Ling Huang, Chih-Yi Ho, Hsin-Ju Chiang, Hsin-Ying Lu, Chun-Chieh Wang, Jiun-Jie Wang, Shu-Hang Ng, Chyong-Huey Lai and 1 more

Abstract read
In one paragraph

Article in Insights into imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Endometrial cancer risk stratification using MRI radiomics: corroborating with choline metabolism.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  8. Cervical cancer segmentation based on medical images: a literature review.Quantitative imaging in medicine and surgery · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yu-Chun LinDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Keelung, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan.
Yenpo LinDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Keelung, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan.
Yen-Ling HuangDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Keelung, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan.
Chih-Yi HoDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Keelung, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan.
Hsin-Ju ChiangDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Keelung, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan.
Hsin-Ying LuDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Keelung, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan.
Chun-Chieh WangDepartment of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, 33302, Taiwan.
Jiun-Jie WangDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Keelung, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan.
Shu-Hang NgDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Keelung, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan.
Chyong-Huey LaiGynecologic Cancer Research Center, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou and Chang Gung University, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan.
Gigin LinDepartment of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou and Keelung, 5 Fuhsing St., Guishan, Taoyuan, 33382, Taiwan. giginlin@cgmh.org.tw.ORCID http://orcid.org/0000-0001-7246-1058

Funding

Chang Gung Memorial Hospital CLRPG3K0023Chang Gung Memorial Hospital CMRPG3I0141Chang Gung Memorial Hospital CMRPG3J1631Chang Gung Memorial Hospital CMRPG3L1601Chang Gung Memorial Hospital CMRPG3M0731Chang Gung Memorial Hospital SMRPG3K0053Ministry of Science and Technology, Taiwan 111-2314-B-182A-041Ministry of Science and Technology, Taiwan MOST 109-2314-B-182A-045Ministry of Science and Technology, Taiwan MOST 110-2628-B-182A-018Ministry of Science and Technology, Taiwan MOST 111-2628-B-182A-012
6 · The paper itself

Abstract

purposeTo investigate the generalizability of transfer learning (TL) of automated tumor segmentation from cervical cancers toward a universal model for cervical and uterine malignancies in diffusion-weighted magnetic resonance imaging (DWI).

methodsIn this retrospective multicenter study, we analyzed pelvic DWI data from 169 and 320 patients with cervical and uterine malignancies and divided them into the training (144 and 256) and testing (25 and 64) datasets, respectively. A pretrained model was established using DeepLab V3 + from the cervical cancer dataset, followed by TL experiments adjusting the training data sizes and fine-tuning layers. The model performance was evaluated using the dice similarity coefficient (DSC).

resultsIn predicting tumor segmentation for all cervical and uterine malignancies, TL models improved the DSCs from the pretrained cervical model (DSC 0.43) when adding 5, 13, 26, and 51 uterine cases for training (DSC improved from 0.57, 0.62, 0.68, 0.70, p < 0.001). Following the crossover at adding 128 cases (DSC 0.71), the model trained by combining data from adding all the 256 patients exhibited the highest DSCs for the combined cervical and uterine datasets (DSC 0.81) and cervical only dataset (DSC 0.91).

conclusionsTL may improve the generalizability of automated tumor segmentation of DWI from a specific cancer type toward multiple types of uterine malignancies especially in limited case numbers.

Indexed as

Deep learningMagnetic resonance imagingUterine neoplasms

Identifiers

PMID36690870
PMCPMC9871146

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.