Evidence map›Paper›PMID 36690867›Full record

ArticleActa neurochirurgica2023

The benefits of automated CSF drainage in normal pressure hydrocephalus.

Sogha Khawari, Maria Kneizeh, Mohamed Elborady, Lewis Thorne, Ahmed Toma, Laurence Watkins

Abstract read
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In one paragraph

Article in Acta neurochirurgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sogha KhawariVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, UCLH, London, UK. sogha.khawari@nhs.net.ORCID 0000-0002-5156-2359
Maria KneizehEast Surrey Hospital, Surrey and Sussex Healthcare NHS Trust, Redhill, Surrey, UK.
Mohamed ElboradyVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, UCLH, London, UK.ORCID 0000-0002-6042-6025
Lewis ThorneVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, UCLH, London, UK.
Ahmed TomaVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, UCLH, London, UK.
Laurence WatkinsVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, UCLH, London, UK.
National Hospital for Neurology and Neurosurgery · GBCairo University · EGEast Surrey Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe commonly used cerebrospinal fluid (CSF) drainage system remains the manual drip-chamber drain. The LiquoGuard (Möller Medical GmbH, Germany) is an automated CSF management device with dual functionality, measuring intracranial pressure and automatic pressure- or volume-led CSF drainage. There is limited research for comparison of devices, particularly in the neurosurgical field, where it has potential to reshape care.

objectiveThis study aims to compare manual drip-chamber drain versus LiquoGuard system, by assessing accuracy of drainage, associated morbidity and impact on length of stay.

methodInclusion criteria consisted of suspected normal pressure hydrocephalus (NPH) patients undergoing extended lumbar drainage. Patients were divided into manual drain group versus automated group.

resultsData was analysed from 42 patients: 31 in the manual group versus 11 in the LiquoGuard group. Volumetric over-drainage was seen in 90.3% (n = 28) versus 0% (p < 0.05), and under-drainage in 38.7% (n = 12) versus 0% (p < 0.05), in the manual and automatic group, respectively. Symptoms of over-drainage were noted in 54.8% (n = 17) of the manual group, all of which had episodes of volumetric over-drainage, versus 18.2% (n = 2) in automated group, of which neither had actual over-drainage (p < 0.05). Higher over-drainage symptoms of manual drain is likely due to increased fluctuation of CSF drainage, instead of smooth CSF drainage seen with LiquoGuard system. An increased length of stay was seen in 38.7% (n = 12) versus 9% (n = 1) (p < 0.05) in the manual and LiquoGuard group, respectively.

conclusionThe LiquoGuard device is a more superior way of CSF drainage in suspected NPH patients, with reduced morbidity and length of stay.

Indexed as

Hydrocephalus, Normal PressureCerebrospinal Fluid LeakGermanyHumansIntracranial PressureAutomated cerebrospinal fluid drainage systemCSFLiquoGuardNormal pressure hydrocephalusNPH

Identifiers

PMID36690867
OpenAlexW4317781529

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.