Evidence map›Paper›PMID 36690826›Full record

ArticleJournal of muscle research and cell motility2024

Nestin expression in intact and hypertrophic myocardium of spontaneously hypertensive rats during aging.

Dana Cizkova, Jitka M Zurmanova, Lucie Gerykova, Alexandros Kouvelas, Mario Heles, Barbara Elsnicova, Frantisek Galatik, Jan Silhavy, Michal Pravenec, Jaroslav Mokry

Open access · hybridAbstract read
In one paragraph

Article in Journal of muscle research and cell motility, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Dana CizkovaDepartment of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
Jitka M ZurmanovaDepartment of Physiology, Faculty of Science, Charles University, Prague, Czech Republic. jitka.zurmanova@natur.cuni.cz.
Lucie GerykovaDepartment of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
Alexandros KouvelasDepartment of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
Mario HelesDepartment of Physiology, Faculty of Science, Charles University, Prague, Czech Republic.
Barbara ElsnicovaDepartment of Physiology, Faculty of Science, Charles University, Prague, Czech Republic.
Frantisek GalatikDepartment of Physiology, Faculty of Science, Charles University, Prague, Czech Republic.
Jan SilhavyInstitute of Physiology, Czech Academy of Sciences, Prague, Czech Republic.
Michal PravenecInstitute of Physiology, Czech Academy of Sciences, Prague, Czech Republic.
Jaroslav MokryDepartment of Histology and Embryology, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
Charles University · CZCzech Academy of Sciences · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nestin is a unique intermediate filament expressed for a short period in the developing heart. It was also documented in several cell types of the adult myocardium under pathological conditions such as myocardial infarction or fibrosis. However, circumstances of nestin re-occurrence in the diseased or aging heart have not been elucidated yet. In this work we immunohistochemically detected nestin to determine its expression and distribution pattern in the left ventricular myocardium of normotensive Wistar Kyoto (WKY) rats and in the hypertrophic ones of spontaneously hypertensive (SHR) rats, both at the age of 1 and 1.5 year. No nestin

Indexed as

AgingMyocardiumNestinAnimalsHypertensionIntermediate Filament ProteinsMaleMyocytes, CardiacNerve Tissue ProteinsRatsRats, Inbred SHRRats, Inbred WKYIntermediate Filament ProteinsNerve Tissue ProteinsNes protein, ratNestinDesminMyocardial hypertrophyMyocardiumNestinVimentin

Identifiers

PMID36690826
PMCPMC11096222
OpenAlexW4317787049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.