ArticleJournal of neurology2023
Comparison of biomarker for diagnosis of nitrous oxide abuse: challenge of cobalamin metabolic parameters, a retrospective study.
Article in Journal of neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Neurophysiological Characteristics of Nitrous Oxide-Induced Polyneuropathy: A Case Series.Journal of the peripheral nervous system : JPNS · 2026Article
- Chronic Nitrous Oxide Exposure Disrupts Metabolism in Mice: A Plasma Untargeted Metabolomics Study.Metabolites · 2026Article
- Review
- Rapid decline of elevated homocysteine level in nitrous oxide use.Scientific reports · 2026Article
- Article
- Nitrous oxide (N2O) recreational use is increasing across Germany - a survey of the German neurological society among practicing neurologists.Neurological research and practice · 2025Article
- Article
- First episode of catatonia followed by a psychotic episode related to chronic nitrous oxide use: A case report.Drug and alcohol review · 2025Article
- Comparative study of subacute combined degeneration of the spinal cord due to nitrous oxide abuse and vitamin B12 deficiency.Frontiers in immunology · 2025Article
- The application and interpretation of laboratory biomarkers for the evaluation of vitamin B12 status.Annals of clinical biochemistry · 2025Review
- Right iliac deep vein thrombosis and pulmonary embolism associated with recreational nitrous oxide: a case report.International journal of emergency medicine · 2024Article
- Enhancing Differential Diagnosis Related to Oxidative Stress, Nitrous Oxide, and Nutrition by Rapid Plasma Homocysteine Measurement.Journal of xenobiotics · 2024Article
- Reply to letter on What biological markers could be used for diagnosis and monitoring of nitrous oxide abuse.European journal of neurology · 2024Article
- What biological markers could be used for diagnosis and monitoring of nitrous oxide abuse?European journal of neurology · 2024Article
- Understanding Neuropathy Features in the Context of Nitrous Oxide Abuse: A Combined Electrophysiological and Metabolic Approach.Biomedicines · 2024Article
- Nitrous oxide abuse in a 21-year-old female: a case report and review of literature.Frontiers in neurology · 2024Review
- Nitrous Oxide Abuse: Clinical Outcomes, Pharmacology, Pharmacokinetics, Toxicity and Impact on Metabolism.Toxics · 2023Review
- Nitrous Oxide Inhalant Abuse: Preliminary Results from a Cross-Sectional Study on Knowledge, Attitudes, and Practices of Italian Physicians (2023).Medicina (Kaunas, Lithuania) · 2023Article
- Vitamin B12 Status in Recreational Users of Nitrous Oxide: A Systematic Review Focusing on the Prevalence of Laboratory Abnormalities.Antioxidants (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecreational use of nitrous oxide (N
methodsWe retrospectively collected clinical and biological data from 52 patients with known, documented chronic N
resultsPlasma homocysteine was almost consistently increased in case of N
conclusionThere is no specific marker of nitrous oxide abuse according to levels of consumption, total vitamin B12 decrease could not be used either as consumption or as severity marker. However, we showed that homocysteine is consistently increased and could be used as marker of recent N
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.