ArticleJournal of neurointerventional surgery2023
Long-term outcomes and dynamic changes of in-stent stenosis after Pipeline embolization device treatment of intracranial aneurysms.
Article in Journal of neurointerventional surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- The role of procedural factors on the outcomes of embolization followed by radiosurgery for the treatment of brain arteriovenous malformations: systematic review and proportional meta-analyses.Acta neurochirurgica · 2024Pooled it
- Safety and efficacy profile of off-label use of the Pipeline Embolization Device: A systematic review and meta-analysis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2024Pooled it
- Nomogram for predicting in-stent stenosis after pipeline embolization device treatment in patients with unruptured intracranial aneurysm: a multicenter model development and validation study.Annals of medicine · 2026Article
- Pipeline Shield versus Pipeline Flex for unruptured intracranial aneurysms: a propensity-matched multicenter study.Neuroradiology · 2026Article
- Comparison of flow diverters versus stent-assisted coiling in unruptured anterior circulation bifurcation aneurysms: a two-center, propensity score matched study.Neurosurgical review · 2026Article
- The role of thrombin time as an independent variable in predicting In-Stent stenosis risk after flow diverter treatment for intracranial aneurysms: a retrospective cohort study.Neurosurgical review · 2025Article
- Subgroup analysis of pipeline Flow-Diverter devices in the treatment of intracranial aneurysms: A long-term real-world study involving 190 patients.Neurosurgical review · 2025Article
- Efficacy and Safety in the Use of Pipeline Vantage Shield Stent versus Pipeline Flex Shield Stent in the Treatment of Patients with Unruptured Intracranial Aneurysms: A Multicenter Study.AJNR. American journal of neuroradiology · 2025Article
- Changes in preoperative and postoperative blood flow parameters are closely associated with in-stent stenosis after flow diverter treatment in unruptured intracranial aneurysms: a retrospective cohort study.Neurosurgical review · 2025Article
- Pipeline embolization device in treating middle cerebral artery aneurysms: a single-center experience in 69 consecutive patients.Neuroradiology · 2025Article
- Distal posterior inferior cerebellar artery (PICA) displacement with end-to-side anastomosis to contralateral PICA: a novel bypass surgery for PICA aneurysm. Illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Subacute Stent Deformities as an Underlying Reason for Vessel Stenosis after Flow Diversion with the p64 Stent: Review and Discussion of Biologic Mechanisms and Consequences.AJNR. American journal of neuroradiology · 2025Article
- Midterm outcomes and costs of Pipeline embolization device alone versus Atlas stent-assisted coiling for unruptured anterior circulation aneurysms: a propensity score matched comparative analysis.Quantitative imaging in medicine and surgery · 2025Article
- Analysis of the effect of platelet function and different doses of ticagrelor after flow diverter treatment of intracranial aneurysms.Neurosurgical review · 2025Article
- Systematic evaluation of neuro-ophthalmic outcomes of the ophthalmic artery covered by flow-diverter.Frontiers in neurology · 2025Review
- Treatment of Unruptured Small and Medium-Sized Wide Necked Aneurysms Using the 64-Wire Surpass Evolve: A Subanalysis From the SEASE International Registry.Journal of the American Heart Association · 2024Observational
- Flow Diversion for Small Branches and Distal Aneurysms of the Posterior Circulation: A Subanalysis of the Post-FD Registry.Stroke (Hoboken, N.J.) · 2024Article
- Comparison of Pipeline embolization device versus Tubridge embolization device in unruptured intracranial aneurysms: a multicenter, propensity score matched study.Journal of neurointerventional surgery · 2024Article
- Predictors of In-Stent Stenosis Following the Implantation of Pipeline Embolization Devices for the Treatment of Aneurysms Located at or beyond the Circle of Willis in the Anterior Circulation.AJNR. American journal of neuroradiology · 2024Article
- Current state of endovascular treatment of anterior cerebral artery aneurysms.Frontiers in neurology · 2024Review
Corrections and comments
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Authors and funding
18 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFlow diverters have revolutionized the treatment of intracranial aneurysms. However, the delayed complications associated with flow diverter use are unknown.
objectiveTo evaluate the incidence, severity, clinical outcomes, risk factors, and dynamic changes associated with in-stent stenosis (ISS) after treatment with a Pipeline embolization device (PED).
methodsPatients who underwent PED treatment between 2015 and 2020 were enrolled. The angiographic, clinical, and follow-up data of 459 patients were independently reviewed by four neuroradiologists to identify ISS. Binary logistic regression was conducted to determine ISS risk factors, and an ISS-time curve was established to demonstrate dynamic changes in ISS after PED implantation.
resultsOf the 459 treated patients, 69 (15.0%) developed ISS. At follow-up, nine patients (2.0%) with ISS demonstrated reversal, while 18 (3.9%) developed parental artery occlusion. A total of 380 patients (82.8%) achieved complete aneurysm occlusion (O'Kelly-Marotta grade D). Patients with posterior-circulation aneurysm (OR=2.895, 95% CI (1.732 to 4.838; P<0.001) or balloon angioplasty (OR=1.992, 95% CI 1.162 to 3.414; P=0.037) were more likely to develop ISS. Patients aged >54 years (OR=0.464, 95% CI 0.274 to 0.785; P=0.006) or with a body mass index of >28 kg/m
conclusionsISS is a common, benign, and self-limiting complication of PED implantation in the Chinese population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.