Evidence map›Paper›PMID 36690086›Full record

ArticleToxicology and applied pharmacology2023

Lung injury and oxidative stress induced by inhaled chlorine in mice is associated with proinflammatory activation of macrophages and altered bioenergetics.

Rama Malaviya, Carol R Gardner, Raymond C Rancourt, Ley Cody Smith, Elena V Abramova, Kinal N Vayas, Andrew J Gow, Jeffrey D Laskin, Debra L Laskin

Open access · greenAbstract read
In one paragraph

Article in Toxicology and applied pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Countermeasures against Pulmonary Threat Agents.The Journal of pharmacology and experimental therapeutics · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Rama MalaviyaDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, USA.
Carol R GardnerDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, USA.
Raymond C RancourtDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, USA.
Ley Cody SmithDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, USA.
Elena V AbramovaDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, USA.
Kinal N VayasDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, USA.
Andrew J GowDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, USA.
Jeffrey D LaskinDepartment of Environmental and Occupational Health and Justice, School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.
Debra L LaskinDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, USA. Electronic address: laskin@eohsi.rutgers.edu.
Rutgers Sexual and Reproductive Health and Rights · NLRutgers, The State University of New Jersey · US

Funding

UMDNJ/Rutgers University CounterACT Research Center of ExcellenceU54AR055073 · NIAMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI LASKIN, JEFFREY D · 2006 to 2024
$71.4M
Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
TRAINING IN EVIRONMENTAL TOXICOLOGYT32ES007148 · NIEHS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI Lauren M Aleksunes · 1987 to 2026
$11.4M
Beckman Coulter MoFlo Astrios EQ Cell SorterS10OD026876 · OD · RUTGERS, THE STATE UNIV OF N.J. · PI LASKIN, DEBRA L · 2019 to 2019
$504k
NIAMS NIH HHS U54 AR055073NIEHS NIH HHS P30 ES005022NIEHS NIH HHS T32 ES007148NIH HHS S10 OD026876
6 · The paper itself

Abstract

Chlorine (Cl

Indexed as

ChlorineLung InjuryAnimalsBronchoalveolar Lavage FluidEnergy MetabolismLungMacrophagesMaleMiceMice, Inbred C57BLOxidative StressChlorineChlorineInflammationLung injuryMacrophagesOxidative stress

Identifiers

PMID36690086
PMCPMC9960611
OpenAlexW4317549048

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.