Evidence map›Paper›PMID 36689369›Full record

ArticleJournal of psychopathology and clinical science2023

Neural correlates of mindful disengagement from worry.

Cecilia A Westbrook, Janine Dutcher, Susan Kusmierski, J David Creswell, Essang Akpan, Lauren S Hallion

Abstract read
In one paragraph

Article in Journal of psychopathology and clinical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cecilia A WestbrookDepartment of Psychiatry.ORCID 0000-0002-6580-729X
Janine DutcherDepartment of Psychology.
Susan KusmierskiDepartment of Psychology.
J David CreswellDepartment of Psychology.
Essang AkpanDepartment of Psychology.
Lauren S HallionDepartment of Psychology.

Funding

Common and Specific Neural Mechanisms of Perseverative Thought in Real-World ContextsK01MH116328 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HALLION, LAUREN S · 2018 to 2022
$876k
NIMH NIH HHS K01 MH116328
6 · The paper itself

Abstract

Uncontrollable worry is a hallmark of generalized anxiety disorder and a transdiagnostic feature of psychopathology. Mindfulness-based strategies show promise for treating worry, but it is unknown which specific strategies are most beneficial, and how these skills might operate on a neurobiological level. We recruited 40 participants with clinically significant worry to undergo functional magnetic resonance imaging while engaging in real-time, idiographic worry and instructed disengagement using two mindfulness strategies (focused attention, acceptance) and one comparison strategy (suppression). Hypotheses were preregistered and partially supported. All disengagement strategies downregulated default mode and upregulated frontoparietal and salience networks, suggesting some shared mechanisms. Focused attention was most effective for promoting disengagement and elicited decreased activity in cognitive control and sensorimotor regions. Successful disengagement was associated with increased activity in rostrolateral prefrontal cortex and functional connectivity between posterior cingulate and primary somatosensory cortex. Findings support the role of cognitive control and somatosensory networks in disengagement from worry and suggest common and distinct mechanisms of disengagement, with focused attention a particularly promising strategy. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Indexed as

MindfulnessAnxietyAnxiety DisordersAttentionHumansPrefrontal Cortex

Identifiers

PMID36689369
PMCPMC11706598

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.