Evidence map›Paper›PMID 36689072›Full record

ReviewTissue engineering and regenerative medicine2023

Silica-Based Advanced Nanoparticles For Treating Ischemic Disease.

Dauletkerey Kudaibergen, Hyun Su Park, Jinwook Park, Gwang-Bum Im, Ju-Ro Lee, Yoon Ki Joung, Suk Ho Bhang, Jae-Hyuk Kim

Open access · greenAbstract readReview
In one paragraph

Review in Tissue engineering and regenerative medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. How Advanced Is Nanomedicine for Atherosclerosis?International journal of nanomedicine · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dauletkerey KudaibergenDepartment of Civil and Environmental Engineering, Pusan National University, Busan, 46241, Republic of Korea.
Hyun Su ParkSchool of Chemical Engineering, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Jinwook ParkDepartment of Civil and Environmental Engineering, Pusan National University, Busan, 46241, Republic of Korea.
Gwang-Bum ImSchool of Chemical Engineering, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Ju-Ro LeeCenter for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoungbuk-Gu, Seoul, 02792, Republic of Korea.
Yoon Ki JoungCenter for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoungbuk-Gu, Seoul, 02792, Republic of Korea.
Suk Ho BhangSchool of Chemical Engineering, Sungkyunkwan University, Suwon, 16419, Republic of Korea. sukhobhang@skku.edu.
Jae-Hyuk KimDepartment of Civil and Environmental Engineering, Pusan National University, Busan, 46241, Republic of Korea. jaehyuk.kim@pusan.ac.kr.
Pusan National University · KRSungkyunkwan University · KRKorea Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, various attempts have been made to apply diverse types of nanoparticles in biotechnology. Silica nanoparticles (SNPs) have been highlighted and studied for their selective accumulation in diseased parts, strong physical and chemical stability, and low cytotoxicity. SNPs, in particular, are very suitable for use in drug delivery and bioimaging, and have been sought as a treatment for ischemic diseases. In addition, mesoporous silica nanoparticles have been confirmed to efficiently deliver various types of drugs owing to their porous structure. Moreover, there have been innovative attempts to treat ischemic diseases using SNPs, which utilize the effects of Si ions on cells to improve cell viability, migration enhancement, and phenotype modulation. Recently, external stimulus-responsive treatments that control the movement of magnetic SNPs using external magnetic fields have been studied. This review addresses several original attempts to treat ischemic diseases using SNPs, including particle synthesis methods, and presents perspectives on future research directions.

Indexed as

Drug CarriersNanoparticlesDrug Delivery SystemsPorositySilicon DioxideDrug CarriersSilicon DioxideBioimagingDrug delivery systemIschemic disease treatmentSilica based magnetic nanoparticleSilica nanoparticle

Identifiers

PMID36689072
PMCPMC10070585
OpenAlexW4317777719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.