Evidence map›Paper›PMID 36689050›Full record

ArticleMolecular biology reports2023

Eukaryotic initiation factor 5A hypusine as a negative regulator of adenosine 2B receptor (A2bAR) through interaction with stem loop sequences within the A2bAR 3'-untranslated region.

Grace Kelly Lee, Chang Wook Kim, Ik-Hyun Cho, Hae-Yeong Kim, Jong Hwan Park

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Grace Kelly Lee *Chingchai Wanidworanun, MD PLLC, 4001 9th St N Suite 228, Arlington, VA, 22203, USA.
Chang Wook Kim *Department of Internal Medicine, College of Medicine, The Catholic University of Korea, #222 Banpo-Daero, Seocho-Gu, Seoul, 06591, South Korea.
Ik-Hyun ChoDepartment of Convergence Medical Science and Institute of Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, 02447, South Korea.
Hae-Yeong KimInstitute of Life Science & Resources and Department of Food Science & Biotechnology, Kyung Hee University, Yongin, 17104, South Korea. hykim@khu.ac.kr.
Jong Hwan ParkResearch Institute of Medical Science, School of Medicine, KonKuk University, 120 Neungdong-Ro, Gwangjin-Gu, Seoul, 05029, South Korea. nihpark@yahoo.com.
Kyung Hee University · KRCatholic University of Korea · KRKonkuk University · KR

Funding

National Research Foundation of Korea NRF-2014R1A1A2058125
6 · The paper itself

Abstract

purposeThe aim of this study was to investigate whether eIF5A hypusine (eIF5A METHODS AND

resultsBased on real-time PCR and western blotting, expression of A2bAR mRNA was significantly decreased upon treatment with eIF5A

conclusionseIF5A

Indexed as

FibroblastsMicroRNAs3' Untranslated RegionsAnimalsGene ExpressionMicePeptide Initiation FactorsReceptors, Purinergic P1RNA, Messenger3' Untranslated RegionsMicroRNAsMirn27 microRNA, mousePeptide Initiation FactorsReceptors, Purinergic P1RNA, MessengerAdenosine 2B receptorC/EBP-βeIF5A hypusineGC7Lipid droplet

Identifiers

PMID36689050
OpenAlexW4317746136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.